A new DNA receptor

一种新的DNA受体

• 批准号: nhmrc : GNT1060522
• 负责人: A/Pr Irina Caminschi
• 金额: $ 63.49万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-dna-receptor/1344735
• 关键词: new; DNA; receptor

The immune system has evolved to fight disease-causing microbes. First, it has to recognize that an infectious agent has invaded. To do this we have developed many probes (receptors) that sense microbial products. Detecting microbial DNA is a critical alarm bell. However, distinguishing pathogen DNA from our own DNA is difficult because both look alike. We have identified a new receptor that helps us identify bacterial DNA and alerts the immune system to the imminent danger.

免疫系统已经进化到可以对抗致病微生物。首先，它必须认识到感染源已经入侵。为此，我们开发了许多探测微生物产物的探针（受体）。检测微生物DNA是一个关键的警钟。然而，区分病原体DNA和我们自己的DNA是困难的，因为两者看起来很相似。我们已经发现了一种新的受体，它可以帮助我们识别细菌DNA，并提醒免疫系统即将到来的危险。