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The identification and characterisation of a new DNA receptor

The identification and characterisation of a new DNA receptor
新DNA受体的鉴定和表征
批准号:
nhmrc : 1060522
负责人:
A/Pr Irina Caminschi
金额:
$43.78万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31

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中文摘要
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英文摘要
The immune system has evolved to fight disease-causing microbes. First, it has to recognize that an infectious agent has invaded. To do this we have developed many probes (receptors) that sense microbial products. Detecting microbial DNA is a critical alarm bell. However, distinguishing pathogen DNA from our own DNA is difficult because both look alike. We have identified a new receptor that helps us identify bacterial DNA and alerts the immune system to the imminent danger.
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The regulatory role of Clec12A in antigen presentation and inflammatory disease
  • 批准号:
    nhmrc : 1142358
  • 项目类别:
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  • 资助金额:
    $93.38万
  • 财政年份:
    2018
  • 负责人:
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  • 依托单位:
The regulatory role of Clec12A in antigen presentation and inflammatory disease
  • 批准号:
    nhmrc : GNT1142358
  • 项目类别:
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  • 资助金额:
    $138.11万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Irina Caminschi
  • 依托单位:
Targeting antigen to Clec9A on dendritic cell for humoral immunity
  • 批准号:
    nhmrc : 1124706
  • 项目类别:
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  • 资助金额:
    $50.82万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Irina Caminschi
  • 依托单位:
Targeting antigen to Clec9A on dendritic cell for humoral immunity
  • 批准号:
    nhmrc : GNT1124706
  • 项目类别:
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  • 资助金额:
    $74.46万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Irina Caminschi
  • 依托单位:
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