The identification and characterisation of a new DNA receptor
The identification and characterisation of a new DNA receptor
批准号:
nhmrc : 1060522
负责人:
A/Pr Irina Caminschi
金额:
$43.78万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31
中文摘要
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英文摘要
The immune system has evolved to fight disease-causing microbes. First, it has to recognize that an infectious agent has invaded. To do this we have developed many probes (receptors) that sense microbial products. Detecting microbial DNA is a critical alarm bell. However, distinguishing pathogen DNA from our own DNA is difficult because both look alike. We have identified a new receptor that helps us identify bacterial DNA and alerts the immune system to the imminent danger.
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财政年份:2018
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负责人:A/Pr Irina Caminschi
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依托单位:
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依托单位:
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财政年份:2017
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依托单位:
Targeting antigen to Clec9A on dendritic cell for humoral immunity
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财政年份:2017
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依托单位:
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项目类别:Project Grants
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财政年份:2015
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负责人:A/Pr Irina Caminschi
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依托单位:
Molecular basis for the efficient processing of antigens taken up by Clec9A, a DAMP receptor on dendritic cells
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依托单位:
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负责人:A/Pr Irina Caminschi
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依托单位:
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批准号:nhmrc : 1060519
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依托单位:
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负责人:A/Pr Irina Caminschi
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依托单位:
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批准号:nhmrc : 575546
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项目类别:NHMRC Project Grants
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资助金额:$35.13万
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财政年份:2009
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负责人:A/Pr Irina Caminschi
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依托单位:
A dendritic cell subset targeting approach for defining immune function and tailoring immunotherapy
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批准号:nhmrc : 516727
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资助金额:$46.19万
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财政年份:2008
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依托单位:
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批准号:nhmrc : 356269
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财政年份:2005
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负责人:A/Pr Irina Caminschi
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依托单位:
海外基金