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EFFECT OF APO A IV 2 ALLELE ON POST PRANDIAL RESPONSE TO DIETARY FAT

EFFECT OF APO A IV 2 ALLELE ON POST PRANDIAL RESPONSE TO DIETARY FAT
APO A IV 2 等位基因对餐后膳食脂肪反应的影响
批准号：
6282796
负责人：
RICHARD B WEINBERG
金额：
$3.63万
依托单位：
WAKE FOREST UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6282796
关键词：
alleles apolipoproteins atherosclerosis blood lipoprotein metabolism cholesterol clinical research dietary lipid disease /disorder proneness /risk genetic susceptibility human subject hyperlipidemia nutrition related tag

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中文摘要
翻译
人类对膳食脂肪和胆固醇的反应是高度可变的。它
英文摘要
The human response to dietary fat and cholesterol is highly variable. It has been observed that the variant allele,apo A-IV-2, attenuates the increase in LDL cholesterol diet, but the mechanism of the allele effect are unknown. The purpose of this study is to find out how this gene affects the metabolism of dietary fat in the bloodstream. Understanding the effect of the apo A-IV-2 allele on diet-induced hyperlipidemia will further elucidate the impact of genetics on the risk for artherosclerosis.
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