Etiology of anxiety, mood and distruptive behavior disorders in adolescence

这是一项关于情绪在青春期精神病理学发展中的作用的生物行为纵向调查。重点是（a）在精神病理学的演变中负面情绪（愤怒、焦虑、悲伤）的多个组成部分（体验、表达、调节）的作用，以及（B）有助于情绪失调和紊乱的社会化经历和生物过程。情绪的失调体验和表达与外化（反社会模式）和内化（焦虑，抑郁情绪）障碍有关。青春期是这些疾病发展的关键时刻，因为在这段时间内精神病理学的发病率增加，临床问题的分化增加。研究了四组青少年（每组N= 60）：（1）共病的外化和内化问题，（2）外化问题占主导地位，（3）内化问题占主导地位，（4）无症状。每组中一半的青年为11-13岁，另一半为14-16岁，以便在每个时间点进行年龄横断面分析。同样数量的男性和女性参与，以检查症状和情绪调节的性别差异。其中一个主题涉及到跨系统的情绪整合，以及不同的情绪模式如何与精神病理学相关。第二个主题涉及疾病如何表现的发展变化，例如疾病的分化沿着性别特异性途径增加。在过去一年中，主要重点是数据收集，实验室会议和家访都接近完成。今年将用于（a）根据Time 1数据编码、分析和准备文章以供发表，以及（B）收集Time 2数据以进行纵向分析。- 情绪和精神病理学;青少年临床问题;共病;性别-人类受试者和人类受试者：仅面试、面试或调查

This is a biobehavioral, longitudinal investigation of the role of emotion in the development of psychopathology in adolescence. The focus is on (a) the role of multiple components (experience, expression, regulation) of negative emotions (anger, anxiety, sadness) in the evolution of psychopathology, and (b) socialization experiences and biological processes that contribute to emotion dysregulation and disorder. The dysregulated experience and expression of emotion is implicated in both externalizing (antisocial patterns) and internalizing (anxiety, depressed mood) disorders. Adolescence is a critical juncture in the development of these disorders because of both the increased incidence of psychopathology during this time period and the increased differentiation of clinical problems. Four groups of youths are studied (N= 60 in each group): (1) comorbid externalizing and internalizing problems, (2) externalizing problems predominate, (3) internalizing problems predominate, (4) asymptomatic. Half the youth in each group are 11-13 years, the other half 14-16 years in order to conduct age cross-sectional analyses at each time point. Equal numbers of males and females participate, in order to examine sex differences in symptoms and emotion regulation. One theme pertains to the integration of emotions across systems, and how different patterns of emotion relate to psychopathology. A second theme pertains to the developmental changes in how disorders are manifested, e.g. increased differentiation of disorder along gender specific pathways. During the past year a primary focus has been on data collection, and both laboratory sessions and home visits are close to complete. This year will be spent (a) coding, analyzing, and preparing articles for publication based on Time 1 data, and (b) collecting the Time 2 data for longitudinal analyses. - emotions & psychopathology; adolescent clinical problems; co-morbidity; gender - Human Subjects & Human Subjects: Interview, Questionaires, or Surveys Only