Etiology of anxiety, mood and distruptive behavior disorders in adolescence

青春期焦虑、情绪和破坏性行为障碍的病因学

• 批准号: 6228061
• 负责人: Carolyn Zahn-Waxler
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6228061
• 关键词: adolescence (12-20); anxiety; behavior disorders; clinical research; disease /disorder etiology; emotions; health surveys; human subject; interview; mental disorders; questionnaires

This is a biobehavioral, longitudinal investigation of the role of emotion in the development of psychopathology in adolescence. The focus is on (a) the role of multiple components (experience, expression, regulation) of negative emotions (anger, anxiety, sadness) in the evolution of psychopathology, and (b) socialization experiences and biological processes that contribute to emotion dysregulation and disorder. The dysregulated experience and expression of emotion is implicated in both externalizing (antisocial patterns) and internalizing (anxiety, depressed mood) disorders. Adolescence is a critical juncture in the development of these disorders because of both the increased incidence of psychopathology during this time period and the increased differentiation of clinical problems. Four groups of youths are studied (N= 60 in each group): (1) comorbid externalizing and internalizing problems, (2) externalizing problems predominate, (3) internalizing problems predominate, (4) asymptomatic. Half the youth in each group are 11-13 years, the other half 14-16 years in order to conduct age cross-sectional analyses at each time point. Equal numbers of males and females participate, in order to examine sex differences in symptoms and emotion regulation. One theme pertains to the integration of emotions across systems, and how different patterns of emotion relate to psychopathology. A second theme pertains to the developmental changes in how disorders are manifested, e.g. increased differentiation of disorder along gender specific pathways. During the past year a primary focus has been on data collection, and both laboratory sessions and home visits are close to complete. This year will be spent (a) coding, analyzing, and preparing articles for publication based on Time 1 data, and (b) collecting the Time 2 data for longitudinal analyses. - emotions & psychopathology; adolescent clinical problems; co-morbidity; gender - Human Subjects & Human Subjects: Interview, Questionaires, or Surveys Only

这是一项关于情绪在青春期精神病理学发展中的作用的生物行为纵向调查。重点是(A)负面情绪(愤怒、焦虑、悲伤)的多个组成部分(经验、表达、调节)在精神病理学演变中的作用，以及(B)导致情绪失调和障碍的社会化经历和生物过程。情绪的失调体验和表达与外化(反社会模式)和内化(焦虑、抑郁情绪)障碍有关。青春期是这些疾病发展的关键时刻，因为在这一时期，精神病理学的发病率增加，临床问题的差异性也增加。研究对象分为四组(每组60人)：(1)内外向问题并存，(2)以外化问题为主，(3)以内化问题为主，(4)无症状。每组中一半的青年年龄在11-13岁，另一半在14-16岁，以便在每个时间点进行年龄横断面分析。同样数量的男性和女性参与，以检查性别在症状和情绪调节方面的差异。一个主题涉及跨系统的情绪整合，以及不同的情绪模式如何与精神病理学相关。第二个主题涉及疾病表现方式的发展变化，例如，沿着性别特有的路径，疾病的分化增加。在过去的一年里，主要的重点是数据收集，实验室会议和家访都已接近完成。今年将花费(A)根据《时代》1号的数据对发表的文章进行编码、分析和准备，以及(B)收集《时间2》的数据进行纵向分析。-情绪和精神病理学；青少年临床问题；共病；性别-人类受试者和人类受试者：仅采访、问卷或调查