A novel role for Alzheimer tau protein in insulin secretion and type 2 diabetes
A novel role for Alzheimer tau protein in insulin secretion and type 2 diabetes
批准号:
nhmrc : GNT1125379
负责人:
A/Pr Sofianos Andrikopoulos
金额:
$102.37万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
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英文摘要
There is a strong association between type 2 diabetes and Alzheimer's disease, however the reason for this is not known. In Azheimer's disease a protein called tau does not function normally and contributes to the declining cognitive function. We have shown that when tau is absent, this lowers blood glucose and reduces the hallmark defects that contribute to type 2 diabetes. By understanding how tau works we may be able to provide better therapeutic agents to treat type 2 diabetes.
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A novel role for Alzheimer tau protein in insulin secretion and type 2 diabetes
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