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Understanding the cause and consequence of impaired insulin secretion in the NZO mouse a model of diabetes.

Understanding the cause and consequence of impaired insulin secretion in the NZO mouse a model of diabetes.
了解糖尿病模型 NZO 小鼠胰岛素分泌受损的原因和后果。
批准号:
nhmrc : 509300
负责人:
A/Pr Sofianos Andrikopoulos
金额:
$47.42万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31

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中文摘要
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英文摘要
Type 2 diabetes is a major health problem affeting over 1 million Australians. A key feature of this disease is reduced secretion of the pancreratic hormone insulin which results in high blood sugar levels. We are using a naturally occurring animal model of diates called the NZO mouse to understand why the pancreas secretes less insulin and the consequences of this defect. This project has the potential of providing better therapeutic strategies for patients with Type 2 diabetes.
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