The role of the novel gene Herpud1 in insulin secretion in Type 2 diabetes

新基因 Herpud1 在 2 型糖尿病胰岛素分泌中的作用

• 批准号: nhmrc : 1003332
• 负责人: A/Pr Sofianos Andrikopoulos
• 金额: $ 33.5万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-novel-gene-2-diabetes/108918
• 关键词: role; novel; gene; Herpud1; insulin

A reduced ability to secrete insulin is the cause of high blood sugar in type 2 diabetes. This study has identified a gene called Herpud1 that affects insulin secretion. By studying the effects of this gene we are improving our knowledge of the defects that occur in Type 2 diabetes. This has the potential of providing better therapeutic strategies and identifying targets for the developments of better drug development.

胰岛素分泌能力降低是2型糖尿病患者高血糖的原因。这项研究已经确定了一种名为Herpud1的基因，它影响胰岛素分泌。通过研究这种基因的影响，我们正在提高我们对2型糖尿病中发生的缺陷的认识。这有可能提供更好的治疗策略，并为更好的药物开发确定目标。