课题基金 / 基金详情

MAD PHASING OF SELENOMETHIONYL CA2+ FREE MANNOSE BINDING PROTEIN C

MAD PHASING OF SELENOMETHIONYL CA2+ FREE MANNOSE BINDING PROTEIN C
硒代甲硫酰 CA2 游离甘露糖结合蛋白 C 的 MAD 定相
批准号:
6658484
负责人:
William I Weis
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28

项目摘要

项目成果

William I Weis的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
C-type lectins are a family of Ca2+-dependent carbohydrate-binding proteins that undergo a reversible conformational change that renders them unable to bind Ca2+, hence carbohydrates, at mildly acid pH. In order to understand this structural transition, we have crystallized the Ca2+-free form of the lectin domain of mannose-binding protein C. We have prepared this protein with selenomethionine substituted for methionine, and we propose to solve the structure by multiwavelength anomalous dispersion phasing of the selenomethionyl protein, using the tuneable 1-5AD beamline to collect the data.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Nanobody- and mini-G protein-enabled molecular pharmacology of HCAR1
  • 批准号:
    10666999
  • 项目类别:
  • 资助金额:
    $15.46万
  • 财政年份:
    2023
  • 负责人:
    William I Weis
  • 依托单位:
Molecular mechanisms of Wnt and mechanical signaling through β-catenin
  • 批准号:
    10404076
  • 项目类别:
  • 资助金额:
    $73.31万
  • 财政年份:
    2019
  • 负责人:
    William I Weis
  • 依托单位:
Molecular mechanisms of Wnt and mechanical signaling through β-catenin
  • 批准号:
    10299581
  • 项目类别:
  • 资助金额:
    $18.83万
  • 财政年份:
    2019
  • 负责人:
    William I Weis
  • 依托单位:
Molecular mechanisms of Wnt and mechanical signaling through β-catenin
  • 批准号:
    10382116
  • 项目类别:
  • 资助金额:
    $2.21万
  • 财政年份:
    2019
  • 负责人:
    William I Weis
  • 依托单位:
海外基金