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CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II

CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II
酵母 RNA 聚合酶 II 的晶体结构
批准号:
6658471
负责人:
PETER R DAVID
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28

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中文摘要
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英文摘要
The proposal covers the collection of high resolution native and heavy atom cluster data for RNA-Polymerase II from yeast. RNA-Polymerase II is responsible for the transcription from DNA to RNA of virtually all of the proteins in eukaryotes. There are now a number of co-crystals, with RNA, DNA, RNA+DNA, amanitin (an inhibitor) and promising heavy atom cluster compounds. Because a single data collection can take 36-40 hours, we have requested a large amount of beam time; however, given the unit cell size and the brightness of the source, the data collections cannot be accomplished in less time. It is expected that as the diffraction to higher resolution improves, more time may be needed, as the data will require two or more sweeps.
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LOW RESOLUTION YEAST RNA POLYMERASE DATA COLLECTION
  • 批准号:
    6586522
  • 项目类别:
  • 资助金额:
    $14.32万
  • 财政年份:
    2002
  • 负责人:
    PETER R DAVID
  • 依托单位:
LOW RESOLUTION YEAST RNA POLYMERASE DATA COLLECTION
  • 批准号:
    6658489
  • 项目类别:
  • 资助金额:
    $14.32万
  • 财政年份:
    2002
  • 负责人:
    PETER R DAVID
  • 依托单位:
LOW RESOLUTION DATA COLLECTION OF YEAST RNA POLYMERASE II (POL II)
  • 批准号:
    6658529
  • 项目类别:
  • 资助金额:
    $14.32万
  • 财政年份:
    2002
  • 负责人:
    PETER R DAVID
  • 依托单位:
CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II
  • 批准号:
    6586504
  • 项目类别:
  • 资助金额:
    $14.32万
  • 财政年份:
    2002
  • 负责人:
    PETER R DAVID
  • 依托单位:
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