CENTER FOR NAVIGATION AND COMMUNICATION SCIENCE

日常生活中最引人注目的特征包括在环境中导航和相互交流的能力。这些功能是生存的基础，但也是最先遇到疾病或老化的神经系统问题的功能之一。罗切斯特大学拥有一套由NIH支持的研究项目，致力于导航和通信背后的感觉、运动和综合机制。这些为新的P-30核心中心提供了一个令人信服的框架，符合NIDCD的使命。成功的关键要素已经到位，包括坚定的领导层、敬业的教师队伍、共享核心服务的先例、咨询和质量保证流程，以及有利于新合作和吸引新调查人员的基础设施。 核心中心将使研究人员能够有效地分享昂贵、耗时、必要但繁琐的研究服务，在许多情况下还可以创新研究服务。计划中有三个研究核心：1)人类学科核心将整合和协调相关项目中受试者的招募、筛选和日程安排；2)研究服务核心将包括一个组织学和成像股(组织准备、图像分析和重建)和一个电子/机械车间(修复和建造实验室部件和设备)；以及3)一个技术和计算核心，将包括一个实验室技术股，该股将实施刺激和行为控制、数据采集和数据分析的自动化实验室系统，而一个补充计算股将支持个人电脑和网络操作、通用软件工具的维护和升级以及工作人员培训。一些研究服务单位现在已经存在，由神经生物学和解剖学系和视觉科学中心(NEI-P3O)共享。新的核心中心将利用我们内在的合作环境，并在增加新承诺的空间所需容量的同时，增强这些设施。其结果将提高所有人的服务质量、效率和多样性。核心中心将产生一个强大的基础设施，将丰富正在进行的和未来的研究的生产力，促进研究人员之间的合作，吸引新的教职员工和学生到该地区，促进进一步的机构支持，并最终为社区和国家的健康做出贡献。

Among the most compelling features of daily life include the ability to navigate through the environment and to communicate with each other. These functions are fundamental to survival, but are also among the first to encounter trouble in the diseased or aging nervous system. The University of Rochester holds a set of NIH- supported research programs dedicated to the sensory, motor, and integrative mechanisms underlying navigation and communication. These provide a compelling framework for a new P-30 Core-Center that matches the mission of the NIDCD. Key ingredients for success for success are in place, including a committed leadership, dedicated faculty, precedents for shared core services, an advisory and quality assurance process, and an infrastructure that is conducive to new collaborations and attractive to new investigators. The Core-Center will allow investigators to efficient share costly, time-consuming, essential but cumbersome, and in many cases innovative research services. Three research cores are planned: 1) a Human Subjects Core will consolidate and coordinate the recruitment, screening, and scheduling of subjects across relevant projects; 2) a Research Services Core will include a Histology & Imaging Unit (tissue preparation, image analysis & reconstruction), and an Electronic/Mechanical Shop (repair and construction of lab components and devices); and 3) a Technology and Computation Core, to include a Lab Technology Unit that will implement automated lab systems for stimulus and behavioral control, data acquisition, and data analysis, while a complementary Computation Unit will support PC and network operations, maintenance & upgrades of common software tools, and staff training. Some research service units exist now, shared between the Department of Neurobiology & Anatomy and the Center for Visual Science (an NEI-P3O). The new Core-Center will exploit our inherently cooperative environment and augment these facilities while adding needed capacity in newly committed space. The result will enhance the quality, efficiency, and diversity of services to all. The Core-Center will generate a robust infrastructure that will enrich the productivity of ongoing and future research, promote collaborations among investigators, attract new faculty and students to the area, facilitate further institutional support, and ultimately contribute to the health of the community and the nation.