CSH CONFERENCE ON AXON GUIDANCE & NEURAL PLASTICITY

描述(申请人摘要)：拟在COLD举行的会议 斯普林港“轴突引导与神经可塑性”实验室将集结 该领域的领导者、初级教师、博士后研究员和研究生 学生讨论该领域的新的、前沿的发展。这项建议 寻求支助两年期系列会议的第二、第三和第四次会议 将在冷泉港实验室举行。会议将讨论的主题 2000年会议包括：一、轴突引导机制，包括分析 指导信号、它们的接收以及它们转换成在 通过调节生长锥体细胞骨架的运动；关于地图的研究 视觉和嗅觉系统的形成以及突触的机制 队形；以及塑性的机制，包括相互关系 学习和神经元连接之间的关系。多样化的实验方法 (例如生物化学和遗传学)和系统(即各种脊椎动物和 无脊椎动物)将被突出显示。与MODEL的基因组序列 生物与人类之间的交流正在迅速接近完成 这一领域的工作者对于开发实验和技术上的 不同有机体的优势追求共同的机制基础 轴突引导和可塑性的基本机制。口头陈述将 由各届会议主席与组织者协商选定。每个人 会议将由该领域的两位顶尖科学家主持。已选择 演讲者将包括研究生、博士后研究员和初级 教职员工。两个专题讲座将提供基本的背景知识。 对促进致力于塑性研究的科学家和 那些致力于轴突引导的人。还将有两个海报展示环节， 许多参与者可以展示他们的作品。这次会议将是中等规模的 我们预计将有大约300人参加。

DESCRIPTION (Applicant's Abstract): The proposed meeting to be held at Cold Spring Harbor Laboratory on "Axon Guidance and Neural Plasticity" will assemble leaders in the field, junior faculty, postdoctoral fellows and graduate students to discuss new, cutting-edge developments in the field. This proposal seeks support for the second, third and fourth of a biennial series of meetings to be held at Cold Spring Harbor Laboratory. Topics to be discussed for the 2000 meeting include: i. Mechanisms of axon guidance including the analysis of guidance signals, their reception and their translation into changes in motility through modulation of the growth cone cytoskeleton; ii. Studies on map formation in the visual and olfactory systems, as well as mechanisms of synapse formation; and iii. Mechanisms of plasticity, including the relationship between learning and neuronal connectivity. Diverse experimental approaches (e.g. biochemistry and genetics) and systems (i.e. various vertebrate and invertebrates) will be highlighted. With the genomic sequences of model organisms and human rapidly approaching completion, communication between workers in this field is essential to exploit the experimental and technical advantages of different organisms to pursue the mechanistic basis of common fundamental mechanisms in axon guidance and plasticity. Oral presentations will be selected by the session chairs in consultation with the organizers. Each session will be chaired by two leading scientists in the field. Selected speakers will include graduate students, postdoctoral fellows and junior faculty. Two special lectures will be presented to provide essential background critical to stimulating discussion between scientists working on plasticity and those working on axon guidance. There will also be two poster sessions where many participants can present their work. The meeting will be of moderate size and we expect about 300 people to attend.