Infrastructure Improvements for the Caribbean Primate R*

加勒比灵长类动物 R* 的基础设施改善

• 批准号: 7000749
• 负责人: Melween I. Martinez
• 金额: $ 400万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-20 至 2014-10-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000749
• 关键词: Caribbean region; Primates; Research Infrastructure

DESCRIPTION (provided by applicant): The purpose of this application is to obtain funds for essential infrastructure improvements to enhance the quality of animal research and care at the Sabana Seca Field Station of the Caribbean Primate Research Center (CPRC). For over 30 years the CPRC has been providing a valuable service to the scientific community by supplying healthy Indian-origin rhesus macaques with known backgrounds and of the same genetic pool for use in studies for numerous diseases that affect humans. For the period between October 2000 and October 2004, the CPRC provided over 600 monkeys to PHS and NIH-sponsored research programs and the demand for this species for biomedical and biodefense research initiatives is expected to increase. The proposed construction is an integral part of a multi-phase master plan to modernize the research support facilities of the CPRC in order to continue providing an adequate supply of quality animals to researchers. The proposed projects include the construction of a new veterinary services facility to replace a small and outdated clinic, the upgrade of the electrical infrastructure, and the purchase, installation and construction of a cage rack washer facility. The anticipated impact of the proposed renovations on the animal care and use program, on the research programs of intramural and extramural investigators, and on biomedical research overall, is substantial. These improvements will assure quality research support by expanding and improving the capability of the CPRC to meet current and projected needs to supply rhesus monkeys for biomedical, biodefense, and behavioral research initiatives of National importance.

描述（由申请人提供）： 本申请的目的是为改善基本基础设施获得资金，以提高加勒比灵长类动物研究中心（CPRC）Sabana Seca野外站的动物研究和护理质量。30多年来，CPRC一直为科学界提供宝贵的服务，提供具有已知背景和相同基因库的健康印度恒河猴，用于研究影响人类的许多疾病。在2000年10月至2004年10月期间，CPRC向PHS和NIH赞助的研究计划提供了600多只猴子，预计生物医学和生物防御研究计划对该物种的需求将增加。拟议的建设是多阶段总体计划的一个组成部分，该计划旨在实现CPRC研究支持设施的现代化，以便继续为研究人员提供充足的优质动物供应。拟议项目包括建造一个新的兽医服务设施以取代一个小型过时的诊所、升级电力基础设施以及购买、安装和建造一个笼架清洗机设施。拟议的翻修对动物护理和使用计划、对校内和校外研究人员的研究计划以及对整体生物医学研究的预期影响是巨大的。这些改进将通过扩大和提高CPRC的能力来确保高质量的研究支持，以满足当前和预计的需求，为国家重要的生物医学，生物防御和行为研究计划提供恒河猴。