CARIBBEAN PRIMATE RESEARCH CENTER

描述（由申请人提供）：这笔拨款将继续为美国国立卫生研究院提供支持，以维持加勒比灵长类动物研究中心（CPRC）。CPRC由四个综合设施组成：(1)圣地亚哥岛，一个独特的自由放养的印度恒河猴（Macaca mulatta）的岛屿殖民地；(2) Sabana Seca野外站，CPRC总部位于圣胡安10英里外，这里饲养着来自圣地亚哥群岛的恒河猴，用于各种户外配置的生物医学和行为研究，这在自由放养的动物身上是不可行的；(3)病毒学和遗传学实验室（LVG），位于圣胡安医学科学校区（MSC）；(4)灵长类动物形态学和遗传学实验室（LPMG），该实验室也位于MSC，并拥有CPRC骨骼收藏，用于遗传，发育，病理和解剖研究的独特非人灵长类动物骨骼组合。如本提案所述，CPRC被组织成四个互补和整合的部门：灵长类资源，病毒学和遗传学，行为和神经科学，以及灵长类形态学和遗传学。本申请要求的资金仅用于维持CPRC灵长类资源的基础设施，这些基础设施用于支持美国各地的许多研究项目。这项核心拨款还将允许CPRC寻求额外的支持，与内地和国际研究人员开展合作研究项目。在美国国立卫生研究院的持续支持下，CPRC将继续是一个重要的国家研究资源，并将能够为美国国立卫生研究院资助的研究项目提供具有明确遗传和病毒学背景的健康印度恒河猴。

DESCRIPTION (provided by applicant): This grant will provide continued NIH support to maintain the Caribbean Primate Research Center (CPRC). The CPRC consists of four integrated facilities: (1) Cayo Santiago, a unique free-ranging island colony of Indian-origin rhesus monkeys (Macaca mulatta); (2) the Sabana Seca Field Station, the CPRC's headquarters located 10 miles outside of San Juan, that houses rhesus monkeys derived from the Cayo Santiago colony in various outdoor configurations for biomedical and behavioral studies that are not feasible on free-ranging animals; (3) the Laboratory of Virology and Genetics (LVG), located on the Medical Sciences Campus (MSC), in San Juan; and (4) the Laboratory of Primate Morphology and Genetics (LPMG), which is also located on the MSC, and houses the CPRC Skeletal Collections, unique assemblages of nonhuman primate skeletons for genetic, developmental, pathological and anatomical research. As described in this proposal, CPRC is organized into four complementary and integrated divisions: Primate Resources, Virology and Genetics, Behavior and Neurosciences, and Primate Morphology & Genetics. Funds are requested in this application only to maintain CPRC basic infrastructure of Primate Resources, which are used to support numerous research projects across the United States. This core grant will also allow CPRC to seek additional support to launch collaborative research projects with mainland and international investigators. With continued NIH support, the CPRC will remain a significant national research resource and will be able to provide healthy Indian-origin rhesus monkeys of defined genetic and virological background to NIH-sponsored research programs.