CPRC Resources

CPRC 资源

• 批准号: 10348649
• 负责人: Melween I. Martinez
• 金额: $ 215.51万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-04-15 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10348649
• 关键词: Acquired Immunodeficiency Syndrome; Affect; Aging; Anatomy; Animals; Applied Research; Area; Atherosclerosis; Behavior; Behavioral; Behavioral Sciences; Biological Warfare; Biology; Biomedical Research; Caribbean region; Caring; Cercopithecine Herpesvirus 1; Collaborations; Collection; Communities; Comparative Study; DNA Sequence; Databases; Dengue; Development; Developmental Biology; Disease; Drug Targeting; Ensure; Exhibits; Funding; Gene Mutation; Genes; Genetic; Genome; Goals; Grant; Head; Health; Human; India; Infrastructure; International; Island; Laboratories; Life Cycle Stages; Macaca; Macaca mulatta; Malaria; Malignant Neoplasms; Medical; Modeling; Monitor; Monkeys; Morphology; Nerve Degeneration; Neurobiology; Neurosciences; Neurosciences Research; Oral health; Orthologous Gene; Pathologic; Pathology; Personal Satisfaction; Physiological; Population; Pre-Clinical Model; Primates; Reproductive Biology; Research; Research Personnel; Research Project Grants; Research Support; Resources; Rhesus; SIV; Science; Simian T-lymphotropic virus 1; Skeleton; Translational Research; Type D Retrovirus; United States National Institutes of Health; Virus; Well in self; base; behavioral study; biodefense; computerized; design; drug development; endometriosis; human disease; improved; intergenerational; member; multidisciplinary; nonhuman primate; operation; programs; reference genome; reproductive; skeletal; stressor; vaccine development; virology

PROJECT SUMMARY/ABSTRACT: The major goal of this application is to improve and maintain the Caribbean Primate Research Center's (CPRC) unique research resources through support of operations, administration, veterinary care and research. The CPRC consists of four integrated facilities: (1) Cayo Santiago Field Station, the most valuable of the CPRC research resources that holds a colony of free-ranging rhesus brought from India to Cayo Santiago (CS) in 1938.; (2) the Sabana Seca Field Station, the CPRC's head quarters located 10 miles outside of San Juan that houses rhesus monkeys derived from Cayo Santiago colony in various outdoor configurations for biomedical and behavioral studies that are not feasible on free-ranging animals; (3) the Laboratory of Virology and Genetics (LVG), located on the Medical Sciences Campus (MSC), in San Juan which support several research initiatives using rhesus monkeys as a model; and (4) the Laboratory of Primate Morphology (LPM), which is also located on the MSC, and houses the CPRC skeletal collections, unique assemblages of nonhuman primate skeletons for genetic, developmental, pathological and anatomical research. As described in this proposal, CPRC is organized into four complementary and integrated divisions: Primate Resources, Virology and Genetics, Behavior and Neurosciences, and Primate Morphology. Funds are requested in this application to maintain CPRC basic infrastructure of Primate Resources, which are used to support numerous research projects locally, national and internationally. This grant will also allow CPRC to continue supporting the Translational Science Initiative (TSI) under the Applied Research Component. A major strength of this TSI is conducting multidisciplinary collaborative studies to establish and validate NHP models for preclinical translational projects related to different human diseases. With continued NIH support, the CPRC will remain a significant national research resource and will be able to provide healthy Indian-origin rhesus monkeys of defined genetic and virological background to NIH-sponsored research programs.

项目总结/文摘: