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DESCRIPTION (provided by applicant): The long-term objectives of this project are to contribute to knowledge about the nature and origins of postpartum psychopathology and parenting difficulties among teenage mothers, and the transactional relationships that heighten future mental health risks for both mother and child. The specific aims are to investigate mental health problems as precursors to teenage pregnancy, risks for postpartum psychopathology and the reciprocal processes between teenage parenting, maternal psychopathology and infant dysregulated behavior and emotions. In order to develop specific expertise required as an independent investigator, this K01 proposal encompasses three training goals for the candidate: (i) to gain a fuller understanding of developmental models of psychopathology specific to teenagers; (ii) to develop skills in the assessment of teenage parenting and infant dysregulation; and (iii) to develop expertise in longitudinal statistical analyses to study developmental phenomena over time. These goals will be achieved in a prospective substudy of a longitudinal, large-scale (n=2,451) investigation of girls' behavioral and emotional development (the Pittsburgh Girls Study: PGS). At the start of the substudy data collection, the girls in the PGS will be ages 11-14 years and 6 annual waves of data will already have been collected using multiple informants. It is estimated that 239 teenagers will become mothers during the K01 award period and that a minimum of 191 will participate in the substudy. Participants will be asked to visit the research laboratory with their infant at 2-3 months and at 12 months post delivery for assessment of maternal mental health, parenting and infant behavior and filming of mother-infant interactions. Information from this project may ultimately improve children's welfare by leading to the development of early interventions to reduce mental health risks for teenage pregnancy, postpartum psychopathology and parenting difficulties among adolescents that have long-term, adverse consequences for offspring.
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Mother-Infant Biobehavioral Synchrony and Postpartum Depression
Preconception and prenatal stress effects on cardiovascular disease risk in black women
Preconception and prenatal stress effects on cardiovascular disease risk in black women - Diversity Supplement
Preconception and prenatal stress effects on cardiovascular disease risk in black women
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海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: