Houston Area Molecular Biophysics Program

休斯顿地区分子生物物理学计划

• 批准号: 7084573
• 负责人: THEODORE G WENSEL
• 金额: $ 27.08万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-30 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7084573
• 关键词: Houston; Area; Molecular; Biophysics; Program

DESCRIPTION (provided by applicant): The Houston Area Molecular Biophysics Program (HAMBP) is a Ph.D. research training program in molecular biophysics involving 52 faculty mentors in six educational/research institutions in the Houston-Galveston area: Baylor College of Medicine, Rice University, University of Houston, University of Texas-Houston Medical School, University of Texas M.D. Anderson Cancer Center, and University of Texas Medical Branch. Because of the large number of faculty, and the large and diverse applicant pool represented by this group of institutions, we propose to increase our number of funded trainees to 12. Students pursue a rigorous course of study in the classroom and in the laboratory. They receive a strong foundation in the fundamentals of Molecular Biophysics, exposure to a broad range of topics, and pursue cutting-edge thesis research in world-class biophysics laboratories. Research areas include x-ray crystallography, macromolecular electron microscopy, fluorescence, magnetic resonance and other types of macromolecular spectroscopy, thermodynamics, kinetics, molecular dynamics, theoretical biophysics, protein folding, nucleic acid structure, molecular recognition, and others. Biological structures studied range in size from peptides and lipid mediators to viruses, transcription complexes, and muscle filaments. Supported trainees have included 4 underrepresented minorities, and have had average GRE scores of 83%tile (Q), 81%tile (A), 79%tile(V), and 71%tile (Adv.), with average undergraduate GPAs of 3.55/4.0. The average number of publications per trainee is 6.4 for past trainees, and 4.6 for all trainees, including many high-profile papers and journal covers. Alumni have secured excellent positions upon completion of training, and continue to perform research at a high level. The Program is administered by a Steering Committee of representatives from all partner institutions, which closely monitors the progress of trainees, and make decisions about admission of applicant students and mentors. HAMBP is one of several highly successful cooperative training and research ventures of the partner institutions, which together represent a larger pool of research resources and trainees than any single institution in the U.S.

描述（由申请人提供）：休斯顿地区分子生物物理学项目（HAMBP）是一个分子生物物理学博士研究培训项目，涉及休斯顿-加尔维斯顿地区6个教育/研究机构的52名教师导师：贝勒医学院、莱斯大学、休斯顿大学、德克萨斯大学休斯顿医学院、德克萨斯大学md安德森癌症中心和德克萨斯大学医学分部。由于教师人数众多，以及这组机构所代表的庞大而多样化的申请人群体，我们建议将资助的学员人数增加到12人。学生们在课堂上和实验室里进行严格的学习。他们获得分子生物物理学基础的坚实基础，接触广泛的主题，并在世界一流的生物物理实验室进行前沿的论文研究。研究领域包括x射线晶体学、大分子电子显微镜、荧光、磁共振等各类大分子光谱学、热力学、动力学、分子动力学、理论生物物理学、蛋白质折叠、核酸结构、分子识别等。研究的生物结构范围从多肽和脂质介质到病毒、转录复合物和肌肉细丝。受资助的学员包括4个未被充分代表的少数民族，他们的平均GRE成绩为83% (Q)、81% (A)、79% (V)和71% (ad)，本科平均绩点为3.55/4.0。过去的学员平均每人发表6.4篇文章，所有学员平均每人发表4.6篇文章，其中包括许多备受瞩目的论文和期刊封面。校友在完成培训后获得了优异的职位，并继续在高水平上进行研究。该计划由所有合作院校的代表组成的指导委员会管理，该委员会密切监督学员的进展，并决定录取申请学生和导师。HAMBP是几个合作机构非常成功的合作培训和研究项目之一，这些合作机构共同代表了比美国任何一个机构更大的研究资源和学员池