Global characterization of the Src-regulated kinome

Src 调节激酶组的整体特征

• 批准号: nhmrc : 1048550
• 负责人: A/Pr Alexander Swarbrick
• 金额: $ 39.43万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/global-characterization-src-regulated-kinome/112023
• 关键词: Global; characterization; Src; regulated; kinome

This proposal aims to use new cutting-edge techniques to globally characterize the impact of a particular cancer-causing gene, or oncogene, on the expression and function of an important family of regulatory proteins, termed kinases, in cancer cells. This will identify proteins critical for cancer cell growth and survival that represent potential targets for therapy.

该提案旨在使用新的尖端技术来全面表征特定致癌基因或癌基因对癌细胞中一个重要的调节蛋白家族（称为激酶）的表达和功能的影响。这将确定对癌细胞生长和存活至关重要的蛋白质，这些蛋白质代表了潜在的治疗靶点。