Regulation of B lymphocyte survival and tumourigenesis by the TRAF2-TRAF3-cIAP signaling complex
Regulation of B lymphocyte survival and tumourigenesis by the TRAF2-TRAF3-cIAP signaling complex
批准号:
nhmrc : 596822
负责人:
A/Pr Alexander Swarbrick
金额:
$29.3万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
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英文摘要
A major contributing factor in the development of cancer is the loss of the normal controls that regulate cell survival. We have identified a group of proteins that control the survival of B cells, the white blood cells responsible for producing the antibodies that fight infections. In this project we will investigate the mechanisms by which these proteins function and how inactivation of their functions can lead to multiple myeloma, an aggressive cancer of antibody producing cells.
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How does ROCK ‘education’ of fibroblasts drive neoplastic progression in the breast?
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项目类别:Project Grants
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财政年份:2018
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依托单位:
Precision medicine for high-risk neuroblastoma
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批准号:nhmrc : 1146817
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Mechanistic and functional analysis of the Id4 proto-oncogene in breast and ovarian cancer
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依托单位:
Mechanistic and functional analysis of the Id4 proto-oncogene in breast and ovarian cancer
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依托单位:
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依托单位:
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批准号:nhmrc : 1048550
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资助金额:$39.43万
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财政年份:2013
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负责人:A/Pr Alexander Swarbrick
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依托单位:
Dissecting the function and therapeutic potential of Hedgehog signaling in breast cancer
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批准号:nhmrc : 1051348
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资助金额:$30.62万
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财政年份:2013
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负责人:A/Pr Alexander Swarbrick
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依托单位:
Cellular and molecular mechanisms of Hedgehog signaling in breast cancer
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批准号:nhmrc : 1050693
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项目类别:Project Grants
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资助金额:$36.8万
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财政年份:2013
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依托单位:
The Hedgehog gene as a new drug target for breast cancer
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资助金额:$43.99万
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财政年份:2013
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负责人:A/Pr Alexander Swarbrick
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依托单位:
Dissecting the function of the Hedgehog-Patched pathway in breast cancer progression
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财政年份:2009
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负责人:A/Pr Alexander Swarbrick
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依托单位:
The role of ID-family HLH proteins in breast cancer
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资助金额:$22.39万
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财政年份:2005
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负责人:A/Pr Alexander Swarbrick
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依托单位:
国内基金
海外基金
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