Precision medicine for high-risk neuroblastoma
Precision medicine for high-risk neuroblastoma
批准号:
nhmrc : GNT1146817
负责人:
A/Pr Alexander Swarbrick
金额:
$66.0万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Despite aggressive treatment, the survival rate for high-risk neuroblastoma patients is below 50%. We recently found that these poor-outcome neuroblastomas have a defect in a key drug response pathway, called the JNK pathway. Standard-of-care neuroblastoma drugs all require the JNK pathway to kill neuroblastoma cells, although we have now identified alternative drugs that do not require JNK. We now plan to demonstrate the efficacy of these drugs in neuroblastomas with a defective JNK pathway.
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Precision medicine for high-risk neuroblastoma
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国内基金
海外基金
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