STUDENT LAB: INSULIN SENSITIVITY FOLLOWING EXERCISE & HIGH FAT OVERFEEDING

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。胰岛素是一种由胰腺产生的激素，可以降低血糖。胰岛素降低血糖的能力在2型糖尿病中降低，在其他情况下也会降低，包括高血压、肥胖和一些血脂紊乱。此外，胰岛素降低血糖的能力会随着摄入大量脂肪而降低，而通过运动得到改善。我们这样做是为了向一年级医科学生展示高脂肪饮食和运动对胰岛素作用的差异。此外，由于医学生将成为他们自己的研究对象，这也教会了医学生关于临床研究和作为一名研究志愿者是什么样的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Insulin is a hormone made by the pancrease which lowers blood sugar. Insulin's ability to lower blood sugar is decreased in type 2 diabetes, and also in other conditions including high blood pressure, obesity, and some blood fat disorders. Also, insulin's ability to lower blood sugar is decreased with eating a lot of fat, and is improved with exercise. We are doing this protocol in order to show first year medical students the differences in insulin action with a high fat diet and with exercise. In addition, as medical students will be their own study subjects, this also teaches medical students about clinical research and what being a research volunteer is like.