CONCURRENT EEG AND FMRI STUDIES IN HUMAN BRAIN ACTIVITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 初步研究表明，结合功能磁共振成像的高空间分辨率和脑电的高时间分辨率，有可能获得大脑活动的非侵入性时空图。合作的研究人员开发了硬件、软件和分析技术，以建立一种设备，使同时进行的脑电和功能磁共振成像记录能够安全和准确地获得。合作的研究人员同时进行了一系列fMRI/EEG实验，研究在高达7T的MRI下人类大脑中事件相关电位的空间位置和时间处理。他们还使用该仪器研究了同时进行功能磁共振成像的猴子的颅内电生理事件。图像引导治疗计划中的Golby博士和Bonmasars博士小组的合作旨在使该系统适用于BWH的术中MRI系统。 项目开始时间：27-SEP-2003项目结束时间：2007-8-31

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Preliminary studies suggest that by combining the high spatial resolution of functional magnetic resonance imaging with the high temporal resolution of electroencephalography it is possible to obtain noninvasive spatiotemporal maps of cerebral activity. The collaborating investigators have developed hardware, software, and analysis techniques to build a device that allows concurrent EEG and fMRI recordings to be obtained safely and accurately. The collaborating investigators have performed a series of simultaneous fMRI/EEG experiments that investigate the spatial location and temporal processing of event-related potentials in the human brain at MRI up to 7T. They have also used the instrumentation to study intracranial electrophysiologic events in monkeys with concurrent fMRI. A collaboration between Dr. Golby in the Image-Guided Therapy Program and Dr. Bonmassars group aims to adapt this system for use in the intra-operative MRI systems at BWH. Project Start: 27-SEP-2003 Project End: 31-AUG-2007