CONCURRENT EEG AND FMRI STUDIES IN HUMAN BRAIN ACTIVITY

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 初步研究表明，通过结合功能磁共振成像的高空间分辨率与脑电图的高时间分辨率，有可能获得无创的大脑活动的时空图。合作的研究人员开发了硬件，软件和分析技术，以建立一个设备，允许同时脑电图和功能磁共振成像记录，以获得安全和准确。合作研究人员进行了一系列同步fMRI/EEG实验，研究了高达7 T的MRI下人类大脑中事件相关电位的空间位置和时间处理。他们还使用该仪器研究了猴子的颅内电生理事件，同时进行了功能磁共振成像。图像引导治疗项目中的Golby博士和Bonmassar博士之间的合作的小组旨在使该系统适用于BWH的术中MRI系统。 项目开始：2003年9月27日项目结束：2007年8月31日

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Preliminary studies suggest that by combining the high spatial resolution of functional magnetic resonance imaging with the high temporal resolution of electroencephalography it is possible to obtain noninvasive spatiotemporal maps of cerebral activity. The collaborating investigators have developed hardware, software, and analysis techniques to build a device that allows concurrent EEG and fMRI recordings to be obtained safely and accurately. The collaborating investigators have performed a series of simultaneous fMRI/EEG experiments that investigate the spatial location and temporal processing of event-related potentials in the human brain at MRI up to 7T. They have also used the instrumentation to study intracranial electrophysiologic events in monkeys with concurrent fMRI. A collaboration between Dr. Golby in the Image-Guided Therapy Program and Dr. Bonmassars group aims to adapt this system for use in the intra-operative MRI systems at BWH. Project Start: 27-SEP-2003 Project End: 31-AUG-2007