Facility Core B--Pulmonary Toxicology

设施核心B——肺毒理学

• 批准号: 7239987
• 负责人: Peter S Thorne
• 金额: $ 23.63万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7239987
• 关键词: Acute; Aerosols; Airway Resistance; Allergens; Animal Model; Animals; Area; Asthma; Behavior; Biological Assay; Biological Markers; Biology; Breathing; Consultations; Core Facility; Development; Devices; Disease; Dose; End Point; Endotoxins; Environmental Health; Evaluation; Exposure to; Funding; Gases; Generations; Goals; Host resistance; Inhalation Exposure; Inhalation Therapy; Inhalation Toxicology; Knockout Mice; Lung; Lung diseases; Maintenance; Measurement; Methodology; Nose; Performance; Physiological; Predisposition; Prevention; Productivity; Property; Research; Research Personnel; Rodent; Sampling; Science; Scientist; Services; Structure of parenchyma of lung; System; Systems Analysis; Testing; Toxicology; Transgenic Organisms; improved; innovation; interest; methacholine; nanoparticulate; novel; post-doctoral training; pre-doctoral; resistance factors; response; toxicant; vapor

The goal of the Pulmonary Toxicology Facility Core (PTF, formerly the Inhalation Toxicology Facility) is to provide the facilities and expertise for EHSRC investigators to enhance the productivity and quality of their pulmonary toxicology research and to assist them in exploring new investigative areas in asthma, pulmonary biology, inhalation toxicology, or aerosol science. In addition, investigators from NIEHS-funded Environmental Health Centers are supported with expertise and assays for evaluation of exposures to asthma triggers. This facility provides assistance for testing hypotheses regarding the: ¿ Pulmonary biology of asthma and other environmental lung diseases; ¿ Development and prevention of environmental lung disease; ¿ Physicochemical properties and behavior of endotoxin, allergens, bioaerosols, and other airborne toxicants; and ¿ Performance of sampling devices commonly used by aerosol scientists and hygienists for environmental assessment.

肺毒理学设施核心（PTF，以前吸入毒理学设施）的目标是