Facility Core B--Pulmonary Toxicology
Facility Core B--Pulmonary Toxicology
批准号:
7239987
负责人:
Peter S Thorne
金额:
$23.63万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-04-01 至 2012-03-31
关键词:
AcuteAerosolsAirway ResistanceAllergensAnimal ModelAnimalsAreaAsthmaBehaviorBiological AssayBiological MarkersBiologyBreathingConsultationsCore FacilityDevelopmentDevicesDiseaseDoseEnd PointEndotoxinsEnvironmental HealthEvaluationExposure toFundingGasesGenerationsGoalsHost resistanceInhalation ExposureInhalation TherapyInhalation ToxicologyKnockout MiceLungLung diseasesMaintenanceMeasurementMethodologyNosePerformancePhysiologicalPredispositionPreventionProductivityPropertyResearchResearch PersonnelRodentSamplingScienceScientistServicesStructure of parenchyma of lungSystemSystems AnalysisTestingToxicologyTransgenic Organismsimprovedinnovationinterestmethacholinenanoparticulatenovelpost-doctoral trainingpre-doctoralresistance factorsresponsetoxicantvapor
中文摘要
肺毒学设施核心(PTF,前身为吸入毒理学设施)的目标是
为EHSRC调查人员提供设施和专业知识,以提高他们的工作效率和质量
肺毒理学研究,并协助他们探索哮喘的新研究领域,
肺部生物学、吸入毒理学或气雾剂科学。此外,NIEHS资助的调查人员
环境健康中心得到专业知识和检测支持,以评估暴露于
哮喘会引发。此工具可帮助测试有关以下各项的假设:
·哮喘和其他环境肺部疾病的肺部生物学;
?环境肺病的发展和预防;
内毒素、过敏原、生物气溶胶和其他空气传播的物理化学性质和行为
有毒物质;以及
?气雾剂科学家和卫生员常用的采样设备的性能
环境评估。
英文摘要
The goal of the Pulmonary Toxicology Facility Core (PTF, formerly the Inhalation Toxicology Facility) is to
provide the facilities and expertise for EHSRC investigators to enhance the productivity and quality of their
pulmonary toxicology research and to assist them in exploring new investigative areas in asthma,
pulmonary biology, inhalation toxicology, or aerosol science. In addition, investigators from NIEHS-funded
Environmental Health Centers are supported with expertise and assays for evaluation of exposures to
asthma triggers. This facility provides assistance for testing hypotheses regarding the:
¿ Pulmonary biology of asthma and other environmental lung diseases;
¿ Development and prevention of environmental lung disease;
¿ Physicochemical properties and behavior of endotoxin, allergens, bioaerosols, and other airborne
toxicants; and
¿ Performance of sampling devices commonly used by aerosol scientists and hygienists for
environmental assessment.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Biological Response Profiles of Selected Engineered Nanomaterials after Perinatal Exposure
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批准号:9769736
-
项目类别:
-
资助金额:$41.17万
-
财政年份:2016
-
负责人:Peter S Thorne
-
依托单位:
Integrative Health Sciences Core
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批准号:8279703
-
项目类别:
-
资助金额:$18.96万
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财政年份:2012
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负责人:Peter S Thorne
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依托单位:
Pilot Project Program
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批准号:8279705
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项目类别:
-
资助金额:$30.01万
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财政年份:2012
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负责人:Peter S Thorne
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依托单位:
Envoronmental Modeling and Exposure Assessment Facility
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批准号:8279708
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项目类别:
-
资助金额:$13.32万
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财政年份:2012
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负责人:Peter S Thorne
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依托单位:
Community Outreach and Education Core
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批准号:8279707
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项目类别:
-
资助金额:$11.65万
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财政年份:2012
-
负责人:Peter S Thorne
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依托单位:
Administrative Core (includes review of Director^s Fund)
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批准号:8279704
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项目类别:
-
资助金额:$25.67万
-
财政年份:2012
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负责人:Peter S Thorne
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依托单位:
Career Development Program
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批准号:8279701
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项目类别:
-
资助金额:$7.66万
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财政年份:2012
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负责人:Peter S Thorne
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依托单位:
Pulmonary Toxicology Facility Core
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批准号:8279694
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项目类别:
-
资助金额:$22.0万
-
财政年份:2012
-
负责人:Peter S Thorne
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依托单位:
Career Development of Environmental Health Investigators
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批准号:8055955
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项目类别:
-
资助金额:$12.79万
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财政年份:2010
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负责人:Peter S Thorne
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依托单位:
Career Development of Environmental Health Investigators
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批准号:7239979
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项目类别:
-
资助金额:$11.8万
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财政年份:2007
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负责人:Peter S Thorne
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依托单位:
Administrative Core
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批准号:7239991
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项目类别:
-
资助金额:$27.65万
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财政年份:2007
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负责人:Peter S Thorne
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依托单位:
Project 6: Airborne Exposures to Semi-volatile Organic Pollutants (The AESOP Study)
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批准号:9249566
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项目类别:
-
资助金额:$28.18万
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财政年份:2006
-
负责人:Peter S Thorne
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依托单位:
Project 7: Assessment of Toxicity and Risk of Inhaled Environmental PCB Mixtures
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批准号:9149269
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项目类别:
-
资助金额:$26.37万
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财政年份:2006
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负责人:Peter S Thorne
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依托单位:
CORE--Inhalation Toxicology
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批准号:7106984
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项目类别:
-
资助金额:$10.38万
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财政年份:2006
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负责人:Peter S Thorne
-
依托单位:
Project 6: Airborne Exposures to Semi-volatile Organic Pollutants (The AESOP Study)
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批准号:9149268
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项目类别:
-
资助金额:$28.93万
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财政年份:2006
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负责人:Peter S Thorne
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依托单位:
CORE--Research Translation
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批准号:7106958
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项目类别:
-
资助金额:$8.07万
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财政年份:2006
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负责人:Peter S Thorne
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依托单位:
Project 6: Characterization of Exposures of Urban and Rural Cohorts to
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批准号:7106955
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项目类别:
-
资助金额:$36.33万
-
财政年份:2006
-
负责人:Peter S Thorne
-
依托单位:
Project 7: Assessment of Toxicity and Risk of Inhaled Environmental PCB Mixtures
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批准号:8919616
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项目类别:
-
资助金额:$25.39万
-
财政年份:2006
-
负责人:Peter S Thorne
-
依托单位:
Project 7: Assessment of Toxicity and Risk of Inhaled Environmental PCB Mixtures
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批准号:9249567
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项目类别:
-
资助金额:$25.23万
-
财政年份:2006
-
负责人:Peter S Thorne
-
依托单位:
The AESOP Study: Airborne Exposures to Semi-volatile Organic Pollutants
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批准号:10559691
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项目类别:
-
资助金额:$26.45万
-
财政年份:2006
-
负责人:Peter S Thorne
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依托单位:
海外基金