课题基金 / 基金详情

Rapid DNA Fingerprinting

Rapid DNA Fingerprinting
快速 DNA 指纹识别
批准号:
EP/G006008/1
负责人:
Philip Bartlett
金额:
$13.09万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2008
资助国家:
英国
项目状态:
已结题
起止时间:
2008 至 --
关键词:

项目摘要

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中文摘要
翻译
我们开发了一种基于微阵列的DNA序列变异分析技术,该技术可以提供比现有阵列方法更高的数据密度,灵敏度至少与基于荧光的方法相同,并且具有便携、准确和快速的特点。该方法基于南安普顿大学在物理和生物有机化学方面的最新发现。更快、更便宜、更准确的检测是所有DNA分析应用和市场正在进行的技术目标,该平台的技术特征为在多种应用中提供商业价值提供了坚实的基础,包括法医DNA分析、大量遗传变异研究和分子诊断。在这些应用中,DNA法医分析提供了通过现有供应商进入市场的最快途径,而所需的技术开发有限,无法带来显著的商业利益。这项技术的应用还有可能在监管、法医和安全环境中的现场测试中开发重要的新市场。该项目将在短期内产生特定于应用的概念证明和商业吸引力,并对现场测试市场进行商业分析。这些将共同提供一个强有力的业务计划和已证实的可行性,使我们能够获得更多的发展资金和/或发展伙伴关系。
英文摘要
We have developed a micro-array based technology for DNA sequence variation analysis that can provide greater data density than current array approaches, with sensitivity at least equal to fluorescence based methods and that is portable, accurate and rapid. The method is based on recent discoveries in physical and bio-organic chemistry at Southampton University.Faster, cheaper more accurate detection is the ongoing technical objective of all DNA analysis applications and markets and the technical features of this platform provide a sound basis for providing commercial value in multiple applications including forensic DNA analysis, high volume research into genetic variation and molecular diagnostics. Of these applications, forensic analysis of DNA provides the fastest route to market through existing providers with limited technical development required to provide significant commercial benefit. This application of the technology also has the potential to develop significant novel markets in onsite testing in custodial, forensic and security settings. This project will generate application specific proof of concept and commercial traction in the near term, and commercial analysis of onsite testing markets. Together these will provide a robust business plan and proven feasibility which will enable us to obtain further development funding and/or development partnerships.
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