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AMYGDALA VS HIPPOCAMPAL BDNF FUNCTION WITH MOLECULAR GENETIC TECHNIQUES

AMYGDALA VS HIPPOCAMPAL BDNF FUNCTION WITH MOLECULAR GENETIC TECHNIQUES
杏仁核与海马 BDNF 功能与分子遗传技术
批准号：
7562621
负责人：
Kerry J Ressler
金额：
$3.16万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-05-01 至 2008-04-30
来源：
https://reporter.nih.gov/project-details/7562621
关键词：
Amygdaloid structureBDNF geneComputer Retrieval of Information on Scientific Projects DatabaseExtinction (Psychology)FrightFundingGenetic TechniquesGrantHippocampus (Brain)InstitutionLentivirus VectorMolecular GeneticsPaperPublishingReportingResearchResearch PersonnelResourcesSiteSourceTransgenic MiceUnited States National Institutes of Healthnovelrecombinase

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal combined a novel lentivirus vector that expresses the Cre recombinase with transgenic mice in which the BDNF gene has been flanked by LoxP sites (Floxed). During the reporting period, we have published three papers related to this topic. We found that hippocampal bdnf and trkB activation within the amygdala are required for the normal extinction of fear.
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THE ROLE OF NEUREGULIN AND ITS RECEPTOR, ERBB4, IN CONDITIONED FEAR LEARNING
  • 批准号：
    7562620
  • 项目类别：
  • 资助金额：
    $3.16万
  • 财政年份：
    2007
  • 负责人：
    Kerry J Ressler
  • 依托单位：
    EMORY UNIVERSITY
GENETIC AND TRAUMA-RELATED RISK FACTORS FOR PTSD
  • 批准号：
    7562648
  • 项目类别：
  • 资助金额：
    $2.37万
  • 财政年份：
    2007
  • 负责人：
    Kerry J Ressler
  • 依托单位：
    EMORY UNIVERSITY
MOLECULAR REGULATION OF GABAA RECEPTORS IN THE AMYGDALA
  • 批准号：
    7562649
  • 项目类别：
  • 资助金额：
    $2.37万
  • 财政年份：
    2007
  • 负责人：
    Kerry J Ressler
  • 依托单位：
    EMORY UNIVERSITY
SYNAPTIC PLASTICITY AND EXTINCTION OF FEAR
  • 批准号：
    7562667
  • 项目类别：
  • 资助金额：
    $2.37万
  • 财政年份：
    2007
  • 负责人：
    Kerry J Ressler
  • 依托单位：
    EMORY UNIVERSITY
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