THE ROLE OF NEUREGULIN AND ITS RECEPTOR, ERBB4, IN CONDITIONED FEAR LEARNING

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这个项目与莫尔豪斯医学院的拜伦福特博士合作，研究了操纵杏仁核内神经调节蛋白（NRG）系统的影响。我们使用了一个floxed NRG小鼠与慢病毒生产Cre以及慢病毒，产生显性负ErbB 4在野生型小鼠检查神经调节蛋白功能和ErbB 4受体功能的杏仁核。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project in collaboration with Byron Ford, PhD, of Morehouse School of Medicine examines the effects of manipulating the neuregulin (NRG) system within the amygdala. We have used a floxed NRG mouse with a Lentivirus producing Cre as well as a lentivirus that produces a dominant-negative ErbB4 in wild-type mice to examine Neuregulin functioning and ErbB4 receptor functioning in amygdala.