Translational Research in Neurobiolgy of Disease Training Program

疾病神经生物学转化研究培训计划

• 批准号: 7882328
• 负责人: WALTER C LOW
• 金额: $ 28.96万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-26 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7882328
• 关键词: Disease; Training Programs; Translational Research

DESCRIPTION (provided by applicant): This proposal is for a training grant, "Translational Research in Neurobiology of Disease", at the University of Minnesota. Trainees of this program are 1) graduate students who are pursuing a Ph.D. degree through the Graduate Program in Neuroscience, 2) postdoctoral fellows, and 3) clinical fellows. The challenge is to train basic neuroscientists who will have an appreciation for clinically relevant problems, and to train clinicians who have an appreciation of the fundamental principals of tools of basic science so that they can work together and accelerate the pace of translational neuroscience. The proposed training program funds predoctoral students during their second year in the Graduate Program in Neuroscience after they have committed to the translational neuroscience track. Postdoctoral fellows and clinical fellows can be funded at any point in their training, but must be committed to training in translational neuroscience. The training program is built around a core of didactic course work that includes a course in Neurobiology of Disease, and a Neuroscience Laboratory summer course for all trainees. These courses are designed to produce a dialog and interactions among basic and clinical neuroscientists to facilitate translational research. A group of over 37 trainers are proposed that reflects the diversity of research techniques in basic and clinical neuroscience, but with a thematic focus on neural degeneration and repair. Research interests range from molecular mechanisms underlying neurodegenerative disorders to therapies involving stem cells and recombinant DNA. Each trainer directs a productive research program and has demonstrated commitment to teaching and training. Representing 11 departments throughout the university, the trainers are united by their participation in the Graduate Program in Neuroscience and translational neuroscience research. The trainees will be provided with a strong, broad foundation in basic and clinical neurosciences upon which to build their translational research careers.

描述（由申请人提供）：

项目成果

The conserved dopaminergic diencephalospinal tract mediates vertebrate locomotor development in zebrafish larvae.

• DOI: 10.1523/jneurosci.1638-12.2012
• 发表时间: 2012-09-26
• 期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
• 作者: Lambert AM;Bonkowsky JL;Masino MA
• 通讯作者: Masino MA

Pairing broadband noise with cortical stimulation induces extensive suppression of ascending sensory activity.

• DOI: 10.1088/1741-2560/12/2/026006
• 发表时间: 2015-04
• 期刊: Journal of neural engineering
• 影响因子: 4
• 作者: Markovitz CD;Hogan PS;Wesen KA;Lim HH
• 通讯作者: Lim HH

Effect size of memory deficits in mice with adult-onset P301L tau expression.

• DOI: 10.1016/j.bbr.2014.06.057
• 发表时间: 2014-10-01
• 期刊: BEHAVIOURAL BRAIN RESEARCH
• 影响因子: 2.7
• 作者: Hunsberger, Holly C.;Rudy, Carolyn C.;Weitzner, Daniel S.;Zhang, Chong;Tosto, David E.;Knowlan, Kevin;Xu, Ying;Reed, Miranda N.
• 通讯作者: Reed, Miranda N.

De novo induction of genetically engineered brain tumors in mice using plasmid DNA.

• DOI: 10.1158/0008-5472.can-08-1800
• 发表时间: 2009-01-15
• 期刊: Cancer research
• 影响因子: 11.2
• 作者: Wiesner SM;Decker SA;Larson JD;Ericson K;Forster C;Gallardo JL;Long C;Demorest ZL;Zamora EA;Low WC;SantaCruz K;Largaespada DA;Ohlfest JR
• 通讯作者: Ohlfest JR

Individual differences in ERP measures of executive function in early childhood: Relation to low-risk preterm birth and parent-reported behavior.

幼儿期执行功能 ERP 测量的个体差异：与低风险早产和父母报告行为的关系。

• DOI: 10.1080/09297049.2018.1540690
• 发表时间: 2019
• 期刊: Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
• 作者: Hodel,AmandaS;Brumbaugh,JaneE;Hunt,RuskinH;VanDenHeuvel,SaraE;Wiltgen,AnikaM;Thomas,KathleenM
• 通讯作者: Thomas,KathleenM