EARLY DISRUPTIVE DISORDER: TWO DEVELOPMENTAL PATTERNS

早期破坏性障碍：两种发展模式

• 批准号: 7951087
• 负责人: Jean Mueller Thomas
• 金额: $ 0.35万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951087
• 关键词: Affective; Behavior; Characteristics; Clinical Research; Cognitive; Comorbidity; Computer Retrieval of Information on Scientific Projects Database; Data; Development; Disease; Funding; Goals; Grant; Institution; Language; Mood Disorders; Motor; Parent-Child Relations; Parents; Patients; Pattern; Research; Research Personnel; Resources; Source; Symptoms; Testing; Toddler; United States National Institutes of Health; aged; neurobehavioral

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this study is to examine the comorbidity between disruptive and other disorders in toddlers aged 24 to 42 months old. The PI will focus on two types of comorbidity: disruptive disorders with affective dysregulation, and disruptive disorders with neurodevelopmental difficulties (cognitive, language, motor, and neurobehavioral). The aim of this study is to take a first step in distinguishing these two developmental patterns of disruptive behavior with cross-sectional data. First the PI plans to explore patterns of symptoms to verify that patients can be reliably classified into two forms of disruptive disorders: Affective/Disruptive and Neurodevelopmental/Disruptive. Second, she will test the association between these two groups of toddlers and healthy controls with characteristics of the parent and the parent-child relationship.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目标是检查24到42个月大的幼儿中破坏性障碍和其他障碍之间的共病。PI将专注于两种类型的共病：具有情感失调的破坏性障碍，以及具有神经发育障碍(认知、语言、运动和神经行为)的破坏性障碍。本研究的目的是用横断面数据来区分这两种破坏性行为的发展模式。首先，PI计划探索症状模式，以验证患者可以可靠地归类为两种形式的破坏性障碍：情感/破坏性和神经发育/破坏性。其次，她将测试这两组蹒跚学步的儿童和具有父母和亲子关系特征的健康对照组之间的关联。