EARLY DISRUPTIVE DISORDER: TWO DEVELOPMENTAL PATTERNS

早期破坏性障碍：两种发展模式

• 批准号: 7717161
• 负责人: Jean Mueller Thomas
• 金额: $ 4.52万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7717161
• 关键词: Affective; Behavior; Characteristics; Cognitive; Comorbidity; Computer Retrieval of Information on Scientific Projects Database; Data; Development; Disease; Funding; Goals; Grant; Institution; Language; Mood Disorders; Motor; Parent-Child Relations; Parents; Patients; Pattern; Research; Research Personnel; Resources; Source; Symptoms; Testing; Toddler; United States National Institutes of Health; aged; neurobehavioral

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this study is to examine the comorbidity between disruptive and other disorders in toddlers aged 24 to 42 months old. The PI will focus on two types of comorbidity: disruptive disorders with affective dysregulation, and disruptive disorders with neurodevelopmental difficulties (cognitive, language, motor, and neurobehavioral). The aim of this study is to take a first step in distinguishing these two developmental patterns of disruptive behavior with cross-sectional data. First the PI plans to explore patterns of symptoms to verify that patients can be reliably classified into two forms of disruptive disorders: Affective/Disruptive and Neurodevelopmental/Disruptive. Second, she will test the association between these two groups of toddlers and healthy controls with characteristics of the parent and the parent-child relationship.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是检查24至42个月大的幼儿中破坏性和其他疾病之间的共病。PI将重点关注两种类型的合并症：伴有情感失调的破坏性障碍和伴有神经发育困难（认知、语言、运动和神经行为）的破坏性障碍。本研究的目的是采取第一步区分这两种发展模式的破坏性行为的横截面数据。首先，PI计划探索症状模式，以验证患者可以可靠地分为两种形式的破坏性疾病：情感/破坏性和神经发育/破坏性。其次，她将测试这两组幼儿和健康对照组与父母和亲子关系特征之间的关联。