Michigan Center for Integrative Approaches to Health Disparities

密歇根健康差异综合方法中心

• 批准号: 8057407
• 负责人: ANA V DIEZ-ROUX
• 金额: $ 139.69万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-18 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8057407
• 关键词: African American; American; Behavioral; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Communities; Data; Databases; Diabetes Mellitus; Documentation; Effectiveness; Effectiveness of Interventions; Heart Diseases; Hispanics; Hypertension; Income; Intervention; Latino; Maintenance; Michigan; Obesity; Outcome; Parents; Physical activity; Policies; Population; Population Heterogeneity; Process; Randomized; Research; Research Design; Research Personnel; Risk Reduction; Stroke; Translating; United States Agency for Healthcare Research and Quality; Work; cardiovascular risk factor; comparative effectiveness; compare effectiveness; effectiveness research; health disparity; high risk; intervention program; longitudinal analysis; mortality; parent grant; racial and ethnic; research study; skills; socioeconomics; therapy design

DESCRIPTION (provided by applicant): The proposed Revision aims to contribute to the elimination of racial, ethnic and socioeconomic disparities in cardiovascular disease (CVD), including hypertension and stroke, the leading cause of death for all Americans, a major contributor to racial disparities in mortality in the U.S., and a priority condition identified by AHRQ. The aims of the Revision are directly related to activities currently underway in the parent grant, and extend them in a way that is complementary and synergistic. Most importantly, it extends the paradigm and work of parent Center to intervention and CER of special relevance to the elimination of health disparities in cardiovascular disease. The specific aims for the Revision are: 1) To compare the effectiveness of three strategies to maintain physical activity and reductions in cardiovascular risk following a baseline intervention to promote physical activity among residents of low-to moderate income, predominantly African American and Latino communities at high risk for obesity, hypertension, diabetes and heart disease; 2) To enhance skills and help build the supply of researchers from health disparities populations, contributing to capacity to conduct comparative effectiveness research within populations at high risk of CVD; 3) To enhance capacity to conduct CER by developing a database of comparative effectiveness research studies designed to assess the comparative effectiveness of interventions designed to reduce cardiovascular risk through increased physical activity among African American and Hispanic/Latino populations in the U.S. and 4) To actively disseminate CER findings and develop strategies to translate findings into interventions, programs and policies regarding maintenance of behavioral change in low to moderate income, racially and ethnically diverse populations at high risk for poor cardiovascular outcomes. The study design for Aim 1 (the research subproject) involves randomization into three maintenance intervention strategies and longitudinal analysis of quantitative data to compare their effectiveness in maintaining physical activity and cardiovascular risk reductions. We will use systematic project documentation to evaluate process and impact of Aims 2-4.

描述（由申请人提供）：拟议的修订旨在促进消除心血管疾病（CVD）的种族、民族和社会经济差异，包括高血压和中风，这是所有美国人死亡的主要原因，也是美国死亡率种族差异的主要原因，以及由AHRQ识别的优先级条件。修订的目标与目前在母赠款下开展的活动直接相关，并以互补和协同的方式扩大这些活动。最重要的是，它扩展了母中心的模式和工作，以干预和CER特别相关的消除心血管疾病的健康差距。修订的具体目标是：1）比较三种策略的有效性，以保持身体活动和降低心血管风险，在基线干预后，促进中低收入居民的身体活动，主要是非洲裔美国人和拉丁美洲社区的肥胖，高血压，糖尿病和心脏病的高风险; 2）提高技能，帮助建立来自健康差距人群的研究人员供应， 在心血管疾病高危人群中进行比较有效性研究的能力; 3） 通过开发一个比较有效性研究数据库来提高进行CER的能力，该数据库旨在评估旨在通过增加美国非裔美国人和西班牙裔/拉丁裔人群的体力活动来降低心血管风险的干预措施的比较有效性，以及4）积极传播CER结果并制定将结果转化为干预措施的策略，关于维持中低收入、种族和民族多样化、心血管不良结局高风险人群的行为改变的计划和政策。目标1（研究子项目）的研究设计包括随机分为三种维持干预策略和定量数据的纵向分析，以比较它们在维持体力活动和降低心血管风险方面的有效性。我们将使用系统的项目文档来评估目标2-4的过程和影响。