Michigan Center for Integrative Approaches to Health Disparities

描述（由申请人提供）：拟议的修订旨在有助于消除心血管疾病（CVD）的种族，民族和社会经济差异，包括高血压和中风，这是所有美国人死亡的主要原因，也是美国死亡率种族差异的主要原因，也是AHRQ确定的优先条件。修订的目标与母赠款中目前正在进行的活动直接相关，并以一种互补和协同的方式扩展它们。最重要的是，它将家长中心的范例和工作扩展到与消除心血管疾病健康差异特别相关的干预和CER。修订的具体目的是：1)比较三种策略的有效性，以保持身体活动和降低心血管风险后，基线干预，以促进低收入至中等收入的居民，主要是非裔美国人和拉丁裔社区的高肥胖，高血压，糖尿病和心脏病的风险；2)提高技能并帮助建立来自健康差异人群的研究人员供应，做出贡献

DESCRIPTION (provided by applicant): The proposed Revision aims to contribute to the elimination of racial, ethnic and socioeconomic disparities in cardiovascular disease (CVD), including hypertension and stroke, the leading cause of death for all Americans, a major contributor to racial disparities in mortality in the U.S., and a priority condition identified by AHRQ. The aims of the Revision are directly related to activities currently underway in the parent grant, and extend them in a way that is complementary and synergistic. Most importantly, it extends the paradigm and work of parent Center to intervention and CER of special relevance to the elimination of health disparities in cardiovascular disease. The specific aims for the Revision are: 1) To compare the effectiveness of three strategies to maintain physical activity and reductions in cardiovascular risk following a baseline intervention to promote physical activity among residents of low-to moderate income, predominantly African American and Latino communities at high risk for obesity, hypertension, diabetes and heart disease; 2) To enhance skills and help build the supply of researchers from health disparities populations, contributing to capacity to conduct comparative effectiveness research within populations at high risk of CVD; 3) To enhance capacity to conduct CER by developing a database of comparative effectiveness research studies designed to assess the comparative effectiveness of interventions designed to reduce cardiovascular risk through increased physical activity among African American and Hispanic/Latino populations in the U.S. and 4) To actively disseminate CER findings and develop strategies to translate findings into interventions, programs and policies regarding maintenance of behavioral change in low to moderate income, racially and ethnically diverse populations at high risk for poor cardiovascular outcomes. The study design for Aim 1 (the research subproject) involves randomization into three maintenance intervention strategies and longitudinal analysis of quantitative data to compare their effectiveness in maintaining physical activity and cardiovascular risk reductions. We will use systematic project documentation to evaluate process and impact of Aims 2-4.