BIOINFORMATICS CORE

生物信息学核心

• 批准号: 8167429
• 负责人: CAROLYN J HOVDE
• 金额: $ 41.81万
• 依托单位: UNIVERSITY OF IDAHO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167429
• 关键词: Administrator; Area; Arts; Award; Bioinformatics; Biomedical Research; Budgets; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Computer software; Data Storage and Retrieval; Databases; Educational process of instructing; Faculty; Fee-for-Service Plans; Funding; Gene Expression; Grant; High Performance Computing; Human Resources; Idaho; Individual; Institution; Institutional National Research Service Award; Internet; Participant; Phylogenetic Analysis; Power Sources; Process; Proteomics; Research; Research Personnel; Resources; Secure; Signal Transduction; Source; Speed; Statistical Models; Students; System; Telecommunications; Training; United States National Institutes of Health; Universities; Wages; cluster computing; computer cluster; instrumentation; mass spectrometer; protein structure; research facility

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Bioinformatics Core established technological and human resources that support biomedical research in Idaho. Bioinformatics is incorporated into activities at various levels on every Idaho campus as evidenced by separate INBRE bioinformatics budgets by most Network institutions. To maintain critical mass in three types of bioinformatics analyses used in "Cell Signaling" research, areas of emphasis will continue in (i) evolutionary analysis (UI), (ii) gene expression analysis (ISU), and (iii) protein structure analysis and proteomics (BSU). UI will host local databases and a distributed cluster computer for statistical modeling and phylogenetic estimation. ISU will host a distributed cluster computer and software tightly integrated with their high throughput sequencing facility. BSU will host a distributed cluster computer and software tightly integrated with their mass spectrometer facility. Each facility will be available to faculty and students in every state institution via high-speed telecommunications. The high-end computing hardware will remain available to all INBRE participants through secure internet connections and access to state-of-the art analytical software, and experts will provide specialized help as necessary. The facilities received COBRE (UI) or instrumentation (BSU, ISU) awards, substantial material support from each university administration, and support from individual NIH and NSF research awards. In particular, a UI COBRE (LJ Forney, PI), which was recently renewed for five years, will fund additional processing capacity for cluster computing. Bioinformatics hardware and software needs will be optimized statewide for educating and training students and faculty in best-bioinformatics-practices and providing access to specialized high performance computing. Planned upgrades include, at UI, power supplies, servers and cluster nodes, increase disk storage capacity, and transfer of all bioinformatics system administrators to permanent Idaho State salaries; at ISU, computing nodes and data storage and building an integrated bioinformatics teaching/research facility; at BSU, integrating a new mass spectrometer and software, adding two general-purpose servers, increasing data storage capacity, expanding cluster computing capacity, and supporting additional staff on a permanent state line. BSU will also significantly enhance its telecommunications connections by leveraging INBRE funds with NSF instrumentation awards, institutional support, and service fees in individual grants.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 生物信息学核心建立了支持爱达荷州生物医学研究的技术和人力资源。大多数网络机构的单独近亲生物信息学预算证明了生物信息学在每个爱达荷州校园的各个层面的活动中纳入了活动。 为了在“细胞信号传导”研究中使用三种类型的生物信息学分析中保持临界质量，重点将继续（i）进化分析（UI），（ii）基因表达分析（ISU）和（iii）蛋白质结构分析和蛋白质分析（BSU）（BSU）。 UI将托管本地数据库和分布式群集计算机进行统计建模和系统发育估计。 ISU将托管一台分布式的群集计算机和软件，并与其高吞吐量测序设施紧密集成。 BSU将托管一台分布式的群集计算机和软件与质谱仪设施紧密集成。 每个设施都可以通过高速电信为每个州机构的教职员工提供。高端计算硬件将通过安全的Internet连接并访问最先进的分析软件，所有INBRE参与者都将继续使用，专家将在必要时提供专业的帮助。 该设施获得了毛病（UI）或仪器（BSU，ISU）奖项，每个大学管理的大量材料支持以及个人NIH和NSF研究奖的支持。特别是，最近续签了五年的UI Cobre（LJ Forney，PI），将资助集群计算的额外处理能力。 生物信息学硬件和软件需求将在全州优化，以教育和培训学生最佳生物信息学实践的学生和教职员工，并提供对专业高性能计算的访问权限。计划的升级包括在UI，电源，服务器和集群节点，增加磁盘存储容量以及将所有生物信息学系统管理员转移到永久的爱达荷州州工资；在ISU，计算节点和数据存储并构建集成的生物信息学教学/研究设施；在BSU，集成了新的质谱仪和软件，添加了两个通用服务器，增加了数据存储容量，扩大集群计算能力以及在永久状态线上支持其他员工。 BSU还将通过利用NSF仪器奖，机构支持和个人赠款的服务费来大大提高其电信连接。