CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

本分项目是CTSA供资的估计百分比，即 被用于广泛的研究领域(艾滋病研究、儿科研究或 临床试验)。列出的总成本仅是对CTSA金额的估计 用于这一研究领域的基础设施，而不是由 授予子项目或子项目工作人员的NCRR补助金。 为响应RFA-RM-07-007：“机构临床和翻译科学奖”，本修订申请请求支持犹他大学临床和翻译科学中心(CCTS)。我们的CCTS将建立在大学在遗传学和生物信息学方面的优势基础上，并将把临床和翻译研究企业扩展到这两个传统优势领域之外。我们提出了一项计划，以增加大学调查人员与犹他州及周边州公民之间的交流。我们的CCTS提出了五个目标：1)建立一个位于专用空间的学术之家，以支持临床和转化性研究；2)在社区中开发新的和创新的医疗服务和研究计划；3)开发核心服务，以支持尽可能广泛的临床和转化性研究人员；4)为新的研究人员和建立的跨学科团队提供种子资金，以启动临床和转化性项目，这些项目很有可能获得校外资金；5)通过各种教育计划促进新一代临床和转化性研究人员的发展。拟议的CCTS将纳入现有的普通临床研究中心和K30临床研究课程。提出了新的K12和T32教育方案。提出了九项核心资源，包括生物医学信息学、实验设计和生物统计学、监管知识和临床研究伦理、参与者和临床互动资源、转化技术和资源、新的临床和转化方法、试点和合作研究、研究教育、培训和职业发展，最后是社区参与。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. This amended application, in response to RFA-RM-07-007: "Institutional Clinical and Translational Science Award", requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS will build upon the University's strengths in genetics and bioinformatics and will also extend the clinical and translational research enterprises beyond these two areas of traditional strength. We propose a plan to increase the interchange between University investigators and the citizens of Utah and surrounding states. Our CCTS proposes five goals: 1) Establish an academic home, located in a dedicated space, to support clinical and translational research; 2) Develop new and innovative health services and research programs in the community; 3) Develop core services to support the broadest possible spectrum of clinical and translational investigators; 4) Provide seed funds to new investigators and established interdisciplinary teams to initiate clinical and translational projects that have a high likelihood of achieving extramural funding and; 5) Promote the development of a new generation of clinical and translational investigators through a variety of educational programs. The proposed CCTS will incorporate the existing General Clinical Research Center and K30 Clinical Research Curriculum. New K12 and T32 educational programs are proposed. Nine core resources are proposed and include Biomedical Informatics, Experimental Design and Biostatistics, Regulatory Knowledge and Clinical Research Ethics, Participant and Clinical Interactions Resources, Translational Technologies and Resources, Novel Clinical and Translational Methods, Pilot and Collaborative Studies, Research Education, Training and Career Development and finally, Community Engagement.