CTSA INFRASTRUCTURE FOR AIDS RESEARCH

本分项目是CTSA供资的估计百分比，即 被用于广泛的研究领域(艾滋病研究、儿科研究或 临床试验)。列出的总成本仅是对CTSA金额的估计 用于这一研究领域的基础设施，而不是由 授予子项目或子项目工作人员的NCRR补助金。 德克萨斯大学圣安东尼奥分校健康科学中心(UTHSCSA)设立了医学与科学整合研究所(IIMs)，作为临床与转化科学奖(CTSA)的颁奖地点。我们的使命是实现UTHSCSA所有学校以及我们在南得克萨斯州地区的合作组织之间的临床和转化研究、教育、培训和职业发展的最佳整合。研究所将把现有和新开发的资源和智力资本集中在促进临床和转化性研究的学科上，以改善人类健康。有意义的双向社区参与促进了所有利益相关者的接受，随着IIMs的继续发展，这仍将是一项关键原则。研究所的合作伙伴汇集了主要人才和广泛的资源，以创造协同增效作用，为所有参与组织、我们区域的居民和CTSA网络增加价值。关键职能工作组开发了许多创新方法，为研究所、研究人员和方案提供最佳支持。IIMs的显著特点包括：1)与关键的公共和私人组织(学术、医疗、公共卫生、军事)建立了蓬勃发展的伙伴关系；2)在研究资源和基础设施方面进行了重大投资；3)美国最大的军事医疗和生物医学研究行动骨干；4)世界上最大的灵长类研究殖民地之一；5)46,000平方英里的服务区，居民主要是西班牙裔居民，其中包括美国最贫穷的一些人，他们受到高健康差距的困扰，为我们提供了一个机会、挑战和义务，让我们对人类健康产生重大影响。在我们的集体资源、社区焦点和独特的地区人口统计的背景下，我们确定了四个具体目标作为我们CTSA应用的核心要素：目标1-通过提供在我们的合作伙伴中有效集成的全面基础设施来支持变革性临床和转化性研究，以创建多学科临床研究团队；目标2-在现有优势、合作伙伴、多样化的受训者池和强大的教师对指导的奉献精神的基础上，创造培训未来临床和转化型职业研究人员所需的最佳智力环境和培育氛围；目标3-开发基于社区的模型，解决转化研究成果的最佳方法，重点关注我们独特的人口特定风险因素、疾病负担和健康差异；目标4-在所有IIMs计划中实施强大的跟踪和结果评估系统。印度管理学院的使命主要集中在公共卫生上。事实上，我们的主要愿景是与所有合作伙伴密切合作，将我们的学术和社区研究成果转化为我们区域人民的直接利益。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Texas Health Science Center at San Antonio (UTHSCSA) has established the Institute for Integration of Medicine and Science (IIMS) as the home for our Clinical and Translational Science Award [CTSA). Our mission is to achieve optimal integration of clinical and translational research, education, training, and career development across all UTHSCSA schools and among our partner organizations in the South Texas region. IIMS will focus existing and newly developing resources and intellectual capital on advancing the discipline of clinical and translational research for the improvement of human health. Meaningful bidirectional community participation has promoted buy-in from all stakeholders and will remain a key principle as IIMS continues to evolve. IIMS partners have brought together major talent and a broad array of resources to create synergies that add value to all participating organizations, residents of our region and the CTSA network. Key function working groups have developed many innovative approaches to providing optimal support for IIMS investigators and programs. Distinctive features of IIMS include: 1) thriving partnerships with key public and private organizations (academic, health care, public health, military), 2) major investments in research resources and infrastructure, 3) the largest cadre of military health care and biomedical research operations in the US, 4) one of the world's largest primate research colonies, 5) a 46,000 square mile service area populated by predominantly Hispanic residents comprising some of the country's poorest people, plagued by high rates of health disparities, providing an opportunity, challenge and obligation for us to make a significant impact on human health. Within the context of our collective resources, community focus, and unique regional demographics, we have identified four Specific Aims as the core elements of our CTSA application: Aim 1- To support transformative clinical and translational research by providing a comprehensive infrastructure integrated effectively among our partners for the creation of multidisciplinary clinical research teams; Aim 2- To create the optimal intellectual environment and nurturing atmosphere necessary for the training of future clinical and translational career investigators, building upon existing strengths, partnerships, a diverse trainee pool and strong faculty dedication to mentoring; Aim 3- To develop community-based models that address the best means for translating research findings, focusing on our unique population-specific risk factors, disease burdens and health disparities; Aim 4- To implement robust tracking and outcome evaluation systems across all IIMS programs. The mission of IIMS is sharply focused on public health. Indeed, our primary vision is to work closely with all partners to translate the results of our academic and community-based research for the direct benefit of our regional population.