CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365197
• 负责人: ROBERT A CLARK
• 金额: $ 27.44万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365197
• 关键词: Acquired Immunodeficiency Syndrome; Health; Medicine; Research Infrastructure; Research Institute; Science; improved

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Texas Health Science Center at San Antonio (UTHSCSA) has established the Institute for Integration of Medicine and Science (IIMS) as the home for our Clinical and Translational Science Award [CTSA). Our mission is to achieve optimal integration of clinical and translational research, education, training, and career development across all UTHSCSA schools and among our partner organizations in the South Texas region. IIMS will focus existing and newly developing resources and intellectual capital on advancing the discipline of clinical and translational research for the improvement of human health. Meaningful bidirectional community participation has promoted buy-in from all stakeholders and will remain a key principle as IIMS continues to evolve. IIMS partners have brought together major talent and a broad array of resources to create synergies that add value to all participating organizations, residents of our region and the CTSA network. Key function working groups have developed many innovative approaches to providing optimal support for IIMS investigators and programs. Distinctive features of IIMS include: 1) thriving partnerships with key public and private organizations (academic, health care, public health, military), 2) major investments in research resources and infrastructure, 3) the largest cadre of military health care and biomedical research operations in the US, 4) one of the world's largest primate research colonies, 5) a 46,000 square mile service area populated by predominantly Hispanic residents comprising some of the country's poorest people, plagued by high rates of health disparities, providing an opportunity, challenge and obligation for us to make a significant impact on human health. Within the context of our collective resources, community focus, and unique regional demographics, we have identified four Specific Aims as the core elements of our CTSA application: Aim 1- To support transformative clinical and translational research by providing a comprehensive infrastructure integrated effectively among our partners for the creation of multidisciplinary clinical research teams; Aim 2- To create the optimal intellectual environment and nurturing atmosphere necessary for the training of future clinical and translational career investigators, building upon existing strengths, partnerships, a diverse trainee pool and strong faculty dedication to mentoring; Aim 3- To develop community-based models that address the best means for translating research findings, focusing on our unique population-specific risk factors, disease burdens and health disparities; Aim 4- To implement robust tracking and outcome evaluation systems across all IIMS programs. The mission of IIMS is sharply focused on public health. Indeed, our primary vision is to work closely with all partners to translate the results of our academic and community-based research for the direct benefit of our regional population.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 位于圣安东尼奥的德克萨斯大学健康科学中心（UTHSCSA）建立了医学与科学整合研究所（IIMS），作为我们临床和转化科学奖（CTSA）的所在地。我们的使命是实现临床和转化研究，教育，培训和职业发展的最佳整合在所有UTHSCSA学校和我们的合作伙伴组织在南德克萨斯州地区。IIMS将集中现有和新开发的资源和智力资本，推进临床和转化研究的学科，以改善人类健康。有意义的双向社区参与促进了所有利益攸关方的认同，并将继续成为IIMS不断发展的一项关键原则。IIMS合作伙伴汇集了主要人才和广泛的资源，以创造协同效应，为所有参与组织，我们地区的居民和CTSA网络增加价值。关键职能工作组开发了许多创新方法，为IIMS调查人员和项目提供最佳支持。IIMS的显著特点包括：1）与主要公共和私人组织建立蓬勃发展的合作伙伴关系（学术，医疗保健，公共卫生，军事），2）研究资源和基础设施的重大投资，3）美国最大的军事医疗保健和生物医学研究业务，4）世界上最大的灵长类动物研究殖民地之一，5）46，000平方英里的服务区，主要由西班牙裔居民组成，其中包括该国最贫困的一些人，受到健康差距高的困扰，为我们提供了机会，挑战和义务，对人类健康产生重大影响。在我们的集体资源，社区重点和独特的区域人口统计背景下，我们确定了四个具体目标作为我们CTSA申请的核心要素：目标1-通过提供全面的基础设施，支持变革性临床和转化研究，有效地整合我们的合作伙伴，以创建多学科临床研究团队;目标2-为培养未来的临床和翻译职业调查人员创造必要的最佳智力环境和培养氛围，建立现有的优势，伙伴关系，多样化的受训人员库和强大的教师奉献精神指导;目标3-开发以社区为基础的模型，以解决转化研究结果的最佳方法，重点关注我们独特的人群特定风险因素，疾病负担和健康差异;目标4-在所有IIMS计划中实施强大的跟踪和结果评估系统。IIMS的使命集中于公共卫生。事实上，我们的主要愿景是与所有合作伙伴密切合作，将我们的学术和社区研究成果转化为我们区域人口的直接利益。