ZINC AND COPPER EXCRETION AND ABSORPTION IN INFANTS WITH OSTOMIES
造口婴儿的锌和铜排泄和吸收
基本信息
- 批准号:8356699
- 负责人:
- 金额:$ 1.02万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-12-01 至 2011-11-30
- 项目状态:已结题
- 来源:
- 关键词:CeruloplasminClinical ResearchCopperEnteral FeedingEnteral NutritionExcretory functionFundingGrantHourInfantIntestinesMeasuresNational Center for Research ResourcesOstomyOutputPatientsPrincipal InvestigatorResearchResearch InfrastructureResourcesSerumSerum zinc level resultSourceTimeTotal Parenteral NutritionUnited States National Institutes of HealthZincabsorptioncoststable isotope
项目摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
ABSTRACT
We propose to examine the absorption and excretion of zinc and copper in infants with ostomies. This will be accomplished by measuring baseline excretion and serum levels of zinc, copper, and ceruloplasmin, and by utilizing stable isotopes of zinc and copper to measure absorption and excretion. When an infant with an ostomy is receiving primarily total parenteral nutrition (TPN) with minimal or no enteral feeds, we will collect ostomy output for 24 hours to measure zinc and copper excretion, and will measure serum zinc, copper, and ceruloplasmin levels. We will utilize stable isotopes of zinc and copper at two time points: when the infant still has the ostomy and is receiving primarily enteral nutrition without TPN, and lastly, when/if the patients ostomy is removed with the bowels reanastamosed and the patient is stable on enteral feeds.
这个子项目是许多利用资源的研究子项目之一
由NIH/NCRR资助的中心拨款提供。子项目的主要支持
子项目的主要研究者可能是由其他来源提供的,
包括其它NIH来源。 列出的子项目总成本可能
代表子项目使用的中心基础设施的估计数量,
而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。
摘要
我们建议检查锌和铜的吸收和排泄的婴儿与造口术。这将通过测量锌、铜和血浆铜蓝蛋白的基线排泄和血清水平,以及通过利用锌和铜的稳定同位素测量吸收和排泄来实现。当造口术婴儿主要接受全肠外营养(TPN),很少或没有肠内喂养时,我们将收集24小时造口术排出物以测量锌和铜排泄,并测量血清锌、铜和铜蓝蛋白水平。我们将在两个时间点使用锌和铜的稳定同位素:当婴儿仍有造口并主要接受肠内营养而不接受TPN时,以及最后,当/如果患者的造口被移除,肠道重新吻合,并且患者在肠内喂养方面稳定时。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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STEVEN A ABRAMS其他文献
STEVEN A ABRAMS的其他文献
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{{ truncateString('STEVEN A ABRAMS', 18)}}的其他基金
EVALUATION OF THE USE OF DONOR HUMAN MILK FOR INFANTS WITH ABDOMINAL WALL DEFECT
腹壁缺陷婴儿使用供者母乳的评估
- 批准号:
8356736 - 财政年份:2010
- 资助金额:
$ 1.02万 - 项目类别:
EVALUATION OF CALCIUM, VITAMIN D, MAGNESIUM AND ZINC ABSORPTION IN HEALTHY
评估钙、维生素 D、镁和锌的健康吸收情况
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8356713 - 财政年份:2010
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$ 1.02万 - 项目类别:
COMPASSIONATE USE OF AN INTRAVENOUS FAT EMULSION COMPRISED OF FSIH OIL IN THE TR
在 TR 中善意地使用由 FSIH 油组成的静脉脂肪乳剂
- 批准号:
8356700 - 财政年份:2010
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$ 1.02万 - 项目类别:
VITAMIN D STATUS AND IMPACT ON BONE MINERALIZATION IN HUMAN MILK FED HISPANIC
母乳喂养的西班牙裔人的维生素 D 状况及其对骨矿化的影响
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8356696 - 财政年份:2010
- 资助金额:
$ 1.02万 - 项目类别:
QUALITY IMPROVEMENT PROJECT - EVALUATION OF CURRENT STANDARD OF CARE
质量改进项目 - 评估当前护理标准
- 批准号:
8356752 - 财政年份:2010
- 资助金额:
$ 1.02万 - 项目类别:
ZINC AND COPPER EXCRETION AND ABSORPTION IN INFANTS WITH OSTOMIES
造口婴儿的锌和铜排泄和吸收
- 批准号:
8166718 - 财政年份:2009
- 资助金额:
$ 1.02万 - 项目类别:
EVALUATION OF THE USE OF DONOR HUMAN MILK FOR INFANTS WITH ABDOMINAL WALL DEFECT
腹壁缺陷婴儿使用供者母乳的评估
- 批准号:
8166750 - 财政年份:2009
- 资助金额:
$ 1.02万 - 项目类别:
VITAMIN D STATUS AND IMPACT ON BONE MINERALIZATION IN HUMAN MILK FED HISPANIC
母乳喂养的西班牙裔人的维生素 D 状况及其对骨矿化的影响
- 批准号:
8166715 - 财政年份:2009
- 资助金额:
$ 1.02万 - 项目类别:
NUTRITIONAL MANAGEMENT OF INFANTS WITH BRONCHOPULMONARY DYSPLASIA (BPD): EFFE
支气管肺发育不良 (BPD) 婴儿的营养管理:EFFE
- 批准号:
8166685 - 财政年份:2009
- 资助金额:
$ 1.02万 - 项目类别:
Enhancing Dietary Iron and Zinc Bioavailability in Indian Children
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- 批准号:
7923805 - 财政年份:2009
- 资助金额:
$ 1.02万 - 项目类别:
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