ANATOMY AND PHARMACOLOGY OF FEAR-POTENTIATED STARTLE

恐惧增强惊吓的解剖学和药理学

• 批准号: 8357417
• 负责人: MICHAEL NMN DAVIS
• 金额: $ 3.29万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357417
• 关键词: Anatomy; Cues; Diagnosis; Fright; Funding; Grant; Mental Depression; National Center for Research Resources; Patients; Pharmaceutical Preparations; Pharmacology; Post-Traumatic Stress Disorders; Primates; Principal Investigator; Reporting; Research; Research Infrastructure; Resources; Sirolimus; Source; United States National Institutes of Health; conditioning; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. During the reporting period we found that the drug rapamycin blocks consolidation of context but not cue conditioning. We found that patients with PTSD have a selective deficit in inhibition of fear not seen in depression, a major co-morbid diagnosis of PTSD.

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