PUBLISHED JOURNALS ARTICLES FROM THE RESOURCE WITH NO PMCID

来自没有 PMCID 的资源的已发表期刊文章

• 批准号: 8170693
• 负责人: ROBERT M SWEET
• 金额: $ 0.25万
• 依托单位: BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170693
• 关键词: ATP phosphohydrolase; Acids; Active Sites; Adenosine; Agonist; Allergens; Amines; Anabolism; Antibiotics; Antibodies; Antigens; Antineoplastic Agents; Bacteriophages; Binding; Bioavailable; Biochemistry; Bioinformatics; Biotechnology; Bontoxilysin; Cadherins; Catalytic RNA; Cathepsins; Cells; Charge; Chemicals; Chemistry; Chitosan; Clostridium botulinum; Coenzymes; Complex; Computer Retrieval of Information on Scientific Projects Database; Coronavirus; Crystallization; Crystallography; Cyanobacterium; Cyanothece; Cyclic Nucleotides; Cystathionine; Cystic Fibrosis Transmembrane Conductance Regulator; Dependence; Dictyoptera; Dipeptidyl Peptidases; Electrostatics; Enediyne Antitumor Antibiotic; Engineering; Enterococcus faecalis; Enterocytes; Entropy; Enzymes; Epitopes; Fab Immunoglobulins; Family; Feasibility Studies; Ferritin; Fibrinogen; Fimbriae Proteins; Flavin Mononucleotide; Focal Adhesions; Formates; Fructosediphosphate Aldolase; Funding; Gene Expression Regulation; Generations; Glucosaminidase; Glycopeptide Antibiotics; Glycopeptides; Glycoside Hydrolases; Grant; Guanosine; Helicobacter pylori; Heptoses; Homologous Gene; Human; Hybrids; Hydrolysis; Imidazole; Immune; Influenza; Institution; Ions; Ketones; Kidney; Kinetics; Lesion; Ligand Binding; Ligand Binding Domain; Lipid Binding; Lyase; Lysine; Magnesium; Membrane; Metalloproteins; Metals; Methylmercury Compounds; Methyltransferase; Molecular; Molecular Models; Natural Killer Cells; Nitrogen Fixation; Nuclear Pore; Periplasmic Binding Proteins; Phosphoric Monoester Hydrolases; Phosphotransferases; Plasma; Platelet Activating Factor; Polymerase; Potassium Channel; Production; Property; Protein Disulfide Isomerase; Proteins; Pseudomonas aeruginosa; Publishing; RNA-Directed DNA Polymerase; Reaction; Receptor Protein-Tyrosine Kinases; Research; Research Personnel; Resources; Ribonucleases; Ribosomes; Salmonella typhi; Severe Acute Respiratory Syndrome; Signal Transduction; Source; Specificity; Spectrometry; Staging; Structural Models; Structure; Structure-Activity Relationship; Substrate Interaction; Tail; Thymidine; Toxic effect; Transition Elements; United States National Institutes of Health; Virus; Yeasts; Zinostatin; acetoacetate decarboxylase; azetidinone; base; condensin; cupredoxin; decarboxylase inhibitor; design; dimer; electron crystallography; endoplasmic reticulum glycoprotein p72; enzyme substrate; glucosamine 6-phosphate; handbook; inhibitor/antagonist; insight; journal article; lincosamide; molecular dynamics; molecular modeling; multicatalytic endopeptidase complex; mutant; mycobacterial; nitric oxide reductase; novel; orotidylic acid; particle; phosphodiesterase IV; receptor; receptor binding; repair enzyme; response; tool; tumor; urea transporter; vector vaccine; voltage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Below are Published Journals articles followed by their PMIDs, for which PMCIDs have not yet been assigned: crystal structure of fab fragment of an anti-factor ix antibody 10c12 14722079 discoveryof azetidinone acids as conformationally-constrained dual ppara/- agonists 18291645 crystal structure of human factor viii implications for the formation of the factor ixa-factor viiia complex 18400180 structural basis for dsrna recognition by ns1 protein of influenza a virus 18813227 structure of a complex of the atpase seca and theprotein-translocation channel 18923516 design of biaryloxazolidinones as potent orally active antibiotics 18947996 the structure of a transcribing t7 rna polymerase in transition from initiation to elongation 18948533 generation of novel hybrid biaryloxazolidinones as promisingnew antibiotics 18951792 the structural basis of substrate recognition in an exo-b-d-glucosaminidase involved in chitosan hydrolysis 18976664 directing noble metal ion chemistry within a designed ferritin protein 18991401 a group iii periplasmic binding protein 19004000 insights into the mechanism of methylmercury degradation 19004822 structural basis for the inhibition mechanism of human cystathionine --lyase, an enzyme responsible for the production of h2s 19019829 turned on for degradation atpase-independent degradation by clpp 19038348 design, synthesis, and structure-activity relationship, molecular modeling, and nmr studies of aseries of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors 19049349 structures of two major allergens, bla g 4 and per a 4, from cockroaches and their ige binding epitopes 19056737 an antibody loop replacement design feasibility study and a loop-swapped dimer structure 19074157 a fence-like coat for the nuclear pore membrane 19111661 its implication in faster translocation 19118561 a combinedmass spectrometry and bioinformatics approach 19125584 2-aminoimidazoles inhibitors of tgf-b receptor 1 19135364 structural studies of a bacterial condensin complex reveal atp-dependent disruption of intersubunit interactions 19135891 crystallization and preliminary x-ray crystallographic analysis of human plasma platelet activating factor acetylhydrolase 19149681 coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch 19169240 structural basis for dna recognition by the human pax3 homedomain 19199574 structural and chemical basis for glucosamine 6-phosphate binding and activation of the glms ribozyme 19228039 identification and characterization of the lipid-binding property of grlr, a locus of enterocyte effacement regulator 19228114 new insights into the enzyme-substrate interaction 19245227 structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents 19260677 structural insights into immune recognition of the severe acute respiratory syndrome coronavirus s protein receptor binding domain 19324051 structural characterization of the protein cce_0567 from cyanothece 51142, a metalloprotein associated with nitrogen fixation in the duf683 family 19336042 charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase 19354220 crystal structures of free and ligand-bound focal adhesion targeting domain of pyk2 19358827 structure and function of the glycopeptide n-methyltransferase mtfa, a tool for the biosynthesis of modified glycopeptide antibiotics 19389626 the x-ray crystal structure of the phage - tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages 19426744 structure of the noncatalytic domains and global fold of the protein disulfide isomerase erp72 19446521 orally bioavailable alkyl amines 19457666 the origin of the electrostatic perturbation in acetoacetate decarboxylase 19458715 synthesis and crystallographic analysis of 5-se-thymidine dnas 19469515 structural insights into the regulatory particle of the proteasome from methanocaldococcus jannaschii 19481527 aminopiperidine-fused imidazoles as dipeptidyl peptidase-iv inhibitors 19539471 mode of vamp substrate recognition and inhibition of clostridium botulinum neurotoxin f 19543288 combining electron crystallography and x-ray crystallography to study the mlotik1 cyclic nucleotide-regulated potassium channel 19545635 structureof natural killer cell receptor klrg1 bound to e-cadherin reveals basis for mhc-independent missing self recognition 19604491 different vaccine vectors delivering the same antigen elicit cd8+ t cell responses with distinct clonotype and epitope specificity 19620307 a bacterial persistence switch 19622872 salmonella typhi type ivb pilin (pils) and cystic fibrosis transmembrane conductance regulator interaction 19626704 structural understanding of stabilization patternsin engineered bispecific lg-like antibody molecules 19626705 impaired protofibril formation in fibrinogen -n308k is due to altered dd and "aa" interactions 19650644 the selectivity of receptor tyrosine kinase signaling is controlled by a secondary sh2 domain binding site 19665973 the structure of ef-p bound to the 70s ribosome 19696344 molecular basis of substrate promiscuity for the sam-dependent o-methyltransferase ncsb1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin 19702337 structural basis of high-fidelity dna synthesis by yeast dna polymerase delta 19718023 inhibitors selective for mycobacterial versus human proteasomes 19759536 a combined crystallographic and molecular dynamics study of cathepsin l retrobinding inhibitors 19761244 different triggers but related mechanisms 19769984 structural studies on cytosolic domain of magnesium transporter mgte from enterococcus faecalis 19787770 crystal structure of a bacterial homologue of the kidney urea transporter 19865084 characterization of a ras mutant with identical gdp- and gtp-bound structures 19883123 rationally tuning the reduction potential of a single cupredoxin beyond the natural range 19890331 structural characterization of novel pseudomonas aeruginosa type iv pilins 19895819 evidence of kinetic controlof ligand binding and staged product release in mura (enolpyruvyl udp-glcnac synthase)-catalyzed reactions 19899805 a new activity of anti-hiv and anti-tumor protein gap31 dna adenosine glycosidase - structural and modeling insight into its functions 19900411 physical determinants of strong voltage sensitivity of k+ channel block 19915587 a structural basis for the reduced toxicity of dinophysistoxin-2 19916524 rational design of a structural and functional nitric oxide reductase 19940850 helicobacter pylori caga inhibits par1-mark family kinases by mimicking host substrates 19966800 structure of hiv-1 reverse transcriptase with the inhibitor b-thujaplicinol bound at the rnase h active site 20004166 structure and mechanism of the lincosamide antibiotic adenylyltransferase linb 20004168 encounter and extrusion of an intrahelical lesion by a dna repair enzyme 20010681 structure and mechanism of a pentameric formate channel 20010838 synthesis and crystal structure of 2--se-modified guanosine containing dna 20047333 structural and kinetic characterization of the lps biosynthetic enzyme d-alpha,beta-d-heptose-1,7-bisphosphate phosphatase (gmhb) fromescherichia coli 20050699 handbook on cyanobacteria biochemistry, biotechnology and applications, pp 233-57 ha1,2 hypersatellites of 3d transition metals and their photoexcitation energy dependence shell diagram and hypersatellite spectra of 4d transition elements phd thesis synthesis and crystal structure study of 2--se-adenosine-derivatized dna

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 以下是已发表的期刊文章及其 PMID，但尚未为其分配 PMCID： 抗因子 ix 抗体 10c12 的 fab 片段的晶体结构 14722079 发现氮杂环丁酮酸作为构象限制的双 Ppara/- 激动剂 18291645 人因子 viii 的晶体结构对因子 ixa-因子 viiia 复合物形成的影响 18400180 甲型流感病毒 ns1 蛋白识别 dsrna 的结构基础 18813227 atpase seca 和蛋白质易位通道复合物的结构 18923516 作为有效口服活性抗生素的二芳基恶唑烷酮的设计 18947996 从起始到延伸转变的转录 t7 RNA 聚合酶的结构 18948533 作为有前途的新抗生素的新型杂合二芳基恶唑烷酮的产生 18951792 参与壳聚糖水解的外切 b-d-氨基葡萄糖苷酶底物识别的结构基础 18976664 指导设计的铁蛋白内的贵金属离子化学反应 18991401 III组周质结合蛋白19004000 甲基汞降解机制的见解 19004822 人胱硫醚抑制机制的结构基础——裂合酶，一种负责产生 h2s 的酶 19019829 打开降解 clpp 19038348 进行不依赖 atpase 的降解 作为高效和选择性磷酸二酯酶 4 抑制剂的一系列苯基烷基酮的设计、合成和构效关系、分子建模和核磁共振研究 19049349 蟑螂的两种主要过敏原 bla g 4 和 per a 4 的结构及其 ige 结合表位 19056737 抗体环替换设计可行性研究和环交换二聚体结构 19074157 核孔膜的栅栏状涂层 19111661 它对更快易位的影响 19118561 质谱和生物信息学相结合的方法 19125584 2-氨基咪唑 tgf-b 受体抑制剂 1 19135364 细菌凝缩蛋白复合物的结构研究揭示了亚基间相互作用的 atp 依赖性破坏 19135891 人血浆血小板活化因子乙酰水解酶的结晶和初步X射线晶体分析19149681 黄素单核苷酸核糖开关的辅酶识别和基因调控 19169240 人类 pax3 主域 19199574 DNA 识别的结构基础 葡萄糖胺 6-磷酸结合和激活 glms 核酶 19228039 的结构和化学基础 grlr 的脂质结合特性的鉴定和表征，grlr 是肠细胞消失调节因子 19228114 对酶-底物相互作用的新见解 19245227 乳清苷-5'-单磷酸脱羧酶抑制剂作为抗癌剂的构效关系 19260677 严重急性呼吸综合征冠状病毒 S 蛋白受体结合域免疫识别的结构见解 19324051 氰藻 51142 中蛋白质 cce_0567 的结构特征，氰藻是一种与 duf683 家族固氮相关的金属蛋白 19336042 果糖二磷酸醛缩酶中中心赖氨酸残基的电荷稳定和熵减少 19354220 pyk2 的游离和配体结合的粘着斑靶向域的晶体结构 19358827 糖肽 N-甲基转移酶 mtfa 的结构和功能，一种修饰糖肽抗生素生物合成的工具 19389626 噬菌体尾部终止蛋白的 X 射线晶体结构揭示了生物学相关的六聚环结构，并展示了不同长尾噬菌体之间保守的尾部终止机制 19426744 蛋白质二硫键异构酶 erp72 的非催化结构域和整体折叠结构 19446521 口服生物可利用的烷基胺 19457666 乙酰乙酸脱羧酶静电扰动的起源 19458715 5-se-胸苷 DNA 的合成和晶体分析 19469515 对詹纳斯基产甲烷球菌蛋白酶体调节颗粒的结构见解 19481527 作为二肽基肽酶-iv 抑制剂的氨基哌啶稠合咪唑 19539471 鞋面底物识别和抑制肉毒杆菌神经毒素 f 19543288 的模式 结合电子晶体学和 X 射线晶体学研究 mlotik1 环核苷酸调节钾通道 19545635 自然杀伤细胞受体 klrg1 与 e-钙粘蛋白结合的结构揭示了不依赖于 MHC 的缺失自我识别的基础 19604491 传递相同抗原的不同疫苗载体可引发具有不同克隆型和表位特异性的 cd8+ T 细胞反应 19620307 细菌持久性开关 19622872 伤寒沙门氏菌 ivb 型菌毛蛋白 (pils) 与囊性纤维化跨膜电导调节因子相互作用 19626704 对工程双特异性 lg 样抗体分子稳定模式的结构理解 19626705 纤维蛋白原 -n308k 中的原纤维形成受损是由于 dd 和“aa”相互作用改变 19650644 受体酪氨酸激酶信号传导的选择性由二级 sh2 结构域结合位点控制 19665973 与 70 年代核糖体结合的 ef-p 结构 19696344 sam 依赖性邻位甲基转移酶 ncsb1 底物混杂的分子基础，参与烯二炔抗肿瘤抗生素新制癌菌素的生物合成 19702337 酵母 dna 聚合酶 delta 进行高保真 dna 合成的结构基础 19718023 对分枝杆菌与人蛋白酶体具有选择性的抑制剂 19759536 组织蛋白酶 l 逆转录抑制剂的晶体学和分子动力学联合研究 19761244 不同的触发器但相关的机制 19769984 粪肠球菌镁转运蛋白 mgte 胞质结构域的结构研究 19787770 肾尿素转运蛋白细菌同源物的晶体结构 19865084 具有相同 gdp 和 gtp 结合结构的 ras 突变体的表征 19883123 合理调整单个铜氧还蛋白的还原潜力超出自然范围19890331 新型铜绿假单胞菌 iv 型菌毛素的结构表征 19895819 mura（烯醇丙酮酰 udp-glcnac 合酶）催化反应中配体结合和分阶段产物释放的动力学控制的证据 19899805 抗艾滋病毒和抗肿瘤蛋白gap31 dna腺苷糖苷酶的新活性 - 对其功能的结构和建模洞察 19900411 k+ 通道块强电压敏感性的物理决定因素 19915587 Dinophystoxin-2 毒性降低的结构基础 19916524 结构和功能一氧化氮还原酶的合理设计 19940850 幽门螺杆菌 caga 通过模仿宿主底物抑制 par1-mark 家族激酶 19966800 HIV-1 逆转录酶的结构，抑制剂 b-thujaplicinol 结合在核糖核酸酶 h 活性位点 20004166 林可酰胺抗生素腺苷酸转移酶 linb 20004168 的结构和机制 DNA 修复酶 20010681 遇到并挤出螺旋内病变 五聚甲酸盐通道的结构和机制20010838 含DNA 2--se-修饰鸟苷的合成及晶体结构20047333 来自大肠杆菌的 lps 生物合成酶 d-α,β-d-庚糖-1,7-二磷酸磷酸酶 (gmhb) 的结构和动力学表征 20050699 蓝藻生物化学、生物技术和应用手册，第 233-57 页 3d 过渡金属 ha1,2 超卫星及其光激发能量依赖性 4d 过渡元素的壳图和超卫星能谱 博士论文 2-se-腺苷衍生DNA的合成及晶体结构研究