PUBLISHED JOURNALS ARTICLES FROM THE RESOURCE WITH NO PMCID
PUBLISHED JOURNALS ARTICLES FROM THE RESOURCE WITH NO PMCID
批准号:
8170693
负责人:
ROBERT M SWEET
金额:
$0.25万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-07-01 至 2011-06-30
关键词:
ATP phosphohydrolaseAcidsActive SitesAdenosineAgonistAllergensAminesAnabolismAntibioticsAntibodiesAntigensAntineoplastic AgentsBacteriophagesBindingBioavailableBiochemistryBioinformaticsBiotechnologyBontoxilysinCadherinsCatalytic RNACathepsinsCellsChargeChemicalsChemistryChitosanClostridium botulinumCoenzymesComplexComputer Retrieval of Information on Scientific Projects DatabaseCoronavirusCrystallizationCrystallographyCyanobacteriumCyanotheceCyclic NucleotidesCystathionineCystic Fibrosis Transmembrane Conductance RegulatorDependenceDictyopteraDipeptidyl PeptidasesElectrostaticsEnediyne Antitumor AntibioticEngineeringEnterococcus faecalisEnterocytesEntropyEnzymesEpitopesFab ImmunoglobulinsFamilyFeasibility StudiesFerritinFibrinogenFimbriae ProteinsFlavin MononucleotideFocal AdhesionsFormatesFructosediphosphate AldolaseFundingGene Expression RegulationGenerationsGlucosaminidaseGlycopeptide AntibioticsGlycopeptidesGlycoside HydrolasesGrantGuanosineHelicobacter pyloriHeptosesHomologous GeneHumanHybridsHydrolysisImidazoleImmuneInfluenzaInstitutionIonsKetonesKidneyKineticsLesionLigand BindingLigand Binding DomainLipid BindingLyaseLysineMagnesiumMembraneMetalloproteinsMetalsMethylmercury CompoundsMethyltransferaseMolecularMolecular ModelsNatural Killer CellsNitrogen FixationNuclear PorePeriplasmic Binding ProteinsPhosphoric Monoester HydrolasesPhosphotransferasesPlasmaPlatelet Activating FactorPolymerasePotassium ChannelProductionPropertyProtein Disulfide IsomeraseProteinsPseudomonas aeruginosaPublishingRNA-Directed DNA PolymeraseReactionReceptor Protein-Tyrosine KinasesResearchResearch PersonnelResourcesRibonucleasesRibosomesSalmonella typhiSevere Acute Respiratory SyndromeSignal TransductionSourceSpecificitySpectrometryStagingStructural ModelsStructureStructure-Activity RelationshipSubstrate InteractionTailThymidineToxic effectTransition ElementsUnited States National Institutes of HealthVirusYeastsZinostatinacetoacetate decarboxylaseazetidinonebasecondensincupredoxindecarboxylase inhibitordesigndimerelectron crystallographyendoplasmic reticulum glycoprotein p72enzyme substrateglucosamine 6-phosphatehandbookinhibitor/antagonistinsightjournal articlelincosamidemolecular dynamicsmolecular modelingmulticatalytic endopeptidase complexmutantmycobacterialnitric oxide reductasenovelorotidylic acidparticlephosphodiesterase IVreceptorreceptor bindingrepair enzymeresponsetooltumorurea transportervector vaccinevoltage
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Below are Published Journals articles followed by their PMIDs, for which PMCIDs have not yet been assigned:
crystal structure of fab fragment of an anti-factor ix antibody 10c12 14722079
discoveryof azetidinone acids as conformationally-constrained dual ppara/- agonists 18291645
crystal structure of human factor viii implications for the formation of the factor ixa-factor viiia complex 18400180
structural basis for dsrna recognition by ns1 protein of influenza a virus 18813227
structure of a complex of the atpase seca and theprotein-translocation channel 18923516
design of biaryloxazolidinones as potent orally active antibiotics 18947996
the structure of a transcribing t7 rna polymerase in transition from initiation to elongation 18948533
generation of novel hybrid biaryloxazolidinones as promisingnew antibiotics 18951792
the structural basis of substrate recognition in an exo-b-d-glucosaminidase involved in chitosan hydrolysis 18976664
directing noble metal ion chemistry within a designed ferritin protein 18991401
a group iii periplasmic binding protein 19004000
insights into the mechanism of methylmercury degradation 19004822
structural basis for the inhibition mechanism of human cystathionine --lyase, an enzyme responsible for the production of h2s 19019829
turned on for degradation atpase-independent degradation by clpp 19038348
design, synthesis, and structure-activity relationship, molecular modeling, and nmr studies of aseries of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors 19049349
structures of two major allergens, bla g 4 and per a 4, from cockroaches and their ige binding epitopes 19056737
an antibody loop replacement design feasibility study and a loop-swapped dimer structure 19074157
a fence-like coat for the nuclear pore membrane 19111661
its implication in faster translocation 19118561
a combinedmass spectrometry and bioinformatics approach 19125584
2-aminoimidazoles inhibitors of tgf-b receptor 1 19135364
structural studies of a bacterial condensin complex reveal atp-dependent disruption of intersubunit interactions 19135891
crystallization and preliminary x-ray crystallographic analysis of human plasma platelet activating factor acetylhydrolase 19149681
coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch 19169240
structural basis for dna recognition by the human pax3 homedomain 19199574
structural and chemical basis for glucosamine 6-phosphate binding and activation of the glms ribozyme 19228039
identification and characterization of the lipid-binding property of grlr, a locus of enterocyte effacement regulator 19228114
new insights into the enzyme-substrate interaction 19245227
structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents 19260677
structural insights into immune recognition of the severe acute respiratory syndrome coronavirus s protein receptor binding domain 19324051
structural characterization of the protein cce_0567 from cyanothece 51142, a metalloprotein associated with nitrogen fixation in the duf683 family 19336042
charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase 19354220
crystal structures of free and ligand-bound focal adhesion targeting domain of pyk2 19358827
structure and function of the glycopeptide n-methyltransferase mtfa, a tool for the biosynthesis of modified glycopeptide antibiotics 19389626
the x-ray crystal structure of the phage - tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages 19426744
structure of the noncatalytic domains and global fold of the protein disulfide isomerase erp72 19446521
orally bioavailable alkyl amines 19457666
the origin of the electrostatic perturbation in acetoacetate decarboxylase 19458715
synthesis and crystallographic analysis of 5-se-thymidine dnas 19469515
structural insights into the regulatory particle of the proteasome from methanocaldococcus jannaschii 19481527
aminopiperidine-fused imidazoles as dipeptidyl peptidase-iv inhibitors 19539471
mode of vamp substrate recognition and inhibition of clostridium botulinum neurotoxin f 19543288
combining electron crystallography and x-ray crystallography to study the mlotik1 cyclic nucleotide-regulated potassium channel 19545635
structureof natural killer cell receptor klrg1 bound to e-cadherin reveals basis for mhc-independent missing self recognition 19604491
different vaccine vectors delivering the same antigen elicit cd8+ t cell responses with distinct clonotype and epitope specificity 19620307
a bacterial persistence switch 19622872
salmonella typhi type ivb pilin (pils) and cystic fibrosis transmembrane conductance regulator interaction 19626704
structural understanding of stabilization patternsin engineered bispecific lg-like antibody molecules 19626705
impaired protofibril formation in fibrinogen -n308k is due to altered dd and "aa" interactions 19650644
the selectivity of receptor tyrosine kinase signaling is controlled by a secondary sh2 domain binding site 19665973
the structure of ef-p bound to the 70s ribosome 19696344
molecular basis of substrate promiscuity for the sam-dependent o-methyltransferase ncsb1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin 19702337
structural basis of high-fidelity dna synthesis by yeast dna polymerase delta 19718023
inhibitors selective for mycobacterial versus human proteasomes 19759536
a combined crystallographic and molecular dynamics study of cathepsin l retrobinding inhibitors 19761244
different triggers but related mechanisms 19769984
structural studies on cytosolic domain of magnesium transporter mgte from enterococcus faecalis 19787770
crystal structure of a bacterial homologue of the kidney urea transporter 19865084
characterization of a ras mutant with identical gdp- and gtp-bound structures 19883123
rationally tuning the reduction potential of a single cupredoxin beyond the natural range 19890331
structural characterization of novel pseudomonas aeruginosa type iv pilins 19895819
evidence of kinetic controlof ligand binding and staged product release in mura (enolpyruvyl udp-glcnac synthase)-catalyzed reactions 19899805
a new activity of anti-hiv and anti-tumor protein gap31 dna adenosine glycosidase - structural and modeling insight into its functions 19900411
physical determinants of strong voltage sensitivity of k+ channel block 19915587
a structural basis for the reduced toxicity of dinophysistoxin-2 19916524
rational design of a structural and functional nitric oxide reductase 19940850
helicobacter pylori caga inhibits par1-mark family kinases by mimicking host substrates 19966800
structure of hiv-1 reverse transcriptase with the inhibitor b-thujaplicinol bound at the rnase h active site 20004166
structure and mechanism of the lincosamide antibiotic adenylyltransferase linb 20004168
encounter and extrusion of an intrahelical lesion by a dna repair enzyme 20010681
structure and mechanism of a pentameric formate channel 20010838
synthesis and crystal structure of 2--se-modified guanosine containing dna 20047333
structural and kinetic characterization of the lps biosynthetic enzyme d-alpha,beta-d-heptose-1,7-bisphosphate phosphatase (gmhb) fromescherichia coli 20050699
handbook on cyanobacteria biochemistry, biotechnology and applications, pp 233-57
ha1,2 hypersatellites of 3d transition metals and their photoexcitation energy dependence
shell diagram and hypersatellite spectra of 4d transition elements
phd thesis
synthesis and crystal structure study of 2--se-adenosine-derivatized dna
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Life Science and Biomedical technology Research center at NSLS-II LSBR
-
批准号:8744474
-
项目类别:
-
资助金额:$277.34万
-
财政年份:2014
-
负责人:ROBERT M SWEET
-
依托单位:
Life Science and Biomedical technology Research center at NSLS-II LSBR
-
批准号:9306262
-
项目类别:
-
资助金额:$48.0万
-
财政年份:2014
-
负责人:ROBERT M SWEET
-
依托单位:
RAPIDATA AND OTHER THINGS
-
批准号:8363409
-
项目类别:
-
资助金额:$7.66万
-
财政年份:2011
-
负责人:ROBERT M SWEET
-
依托单位:
IMPROVED SOFTWARE AND METHODS FOR DATA COLLECTION
-
批准号:8363412
-
项目类别:
-
资助金额:$17.24万
-
财政年份:2011
-
负责人:ROBERT M SWEET
-
依托单位:
DETECTOR DEVELOPMENT AND UPGRADE
-
批准号:8363410
-
项目类别:
-
资助金额:$17.24万
-
财政年份:2011
-
负责人:ROBERT M SWEET
-
依托单位:
DEVELOP NSLS-II BEAMLINES FOR MACROMOLECULAR CRYSTALLOGRAPHY
-
批准号:8363415
-
项目类别:
-
资助金额:$5.75万
-
财政年份:2011
-
负责人:ROBERT M SWEET
-
依托单位:
MACROMOLECULAR STRUCTURE DETERMINATION - GENERAL USERS
-
批准号:8363359
-
项目类别:
-
资助金额:$130.89万
-
财政年份:2011
-
负责人:ROBERT M SWEET
-
依托单位:
DEVELOP NSLS-II BEAMLINES FOR MACROMOLECULAR CRYSTALLOGRAPHY
-
批准号:8170692
-
项目类别:
-
资助金额:$7.31万
-
财政年份:2010
-
负责人:ROBERT M SWEET
-
依托单位:
RAPIDATA AND OTHER THINGS
-
批准号:8170686
-
项目类别:
-
资助金额:$9.75万
-
财政年份:2010
-
负责人:ROBERT M SWEET
-
依托单位:
TECH R&D CORE SUPPORT FOR AIDS RESEARCH
-
批准号:8170694
-
项目类别:
-
资助金额:$4.37万
-
财政年份:2010
-
负责人:ROBERT M SWEET
-
依托单位:
MACROMOLECULAR STRUCTURE DETERMINATION - GENERAL USERS
-
批准号:8170593
-
项目类别:
-
资助金额:$45.04万
-
财政年份:2010
-
负责人:ROBERT M SWEET
-
依托单位:
IMPROVED SOFTWARE AND METHODS FOR DATA COLLECTION
-
批准号:8170689
-
项目类别:
-
资助金额:$26.82万
-
财政年份:2010
-
负责人:ROBERT M SWEET
-
依托单位:
MACROMOLECULAR STRUCTURE DETERMINATION - GENERAL USERS
-
批准号:7957254
-
项目类别:
-
资助金额:$82.62万
-
财政年份:2009
-
负责人:ROBERT M SWEET
-
依托单位:
RAPIDATA AND OTHER THINGS
-
批准号:7957313
-
项目类别:
-
资助金额:$17.47万
-
财政年份:2009
-
负责人:ROBERT M SWEET
-
依托单位:
Macromolecular Crystallography at the National Synchrotron Light Source
-
批准号:7899411
-
项目类别:
-
资助金额:$85.38万
-
财政年份:2009
-
负责人:ROBERT M SWEET
-
依托单位:
DETECTOR DEVELOPMENT AND UPGRADE
-
批准号:7957314
-
项目类别:
-
资助金额:$8.74万
-
财政年份:2009
-
负责人:ROBERT M SWEET
-
依托单位:
MICRODIFFRACTION ON BEAMLINE X25
-
批准号:7957315
-
项目类别:
-
资助金额:$17.47万
-
财政年份:2009
-
负责人:ROBERT M SWEET
-
依托单位:
THE CENTRAL COMPUTING CORE
-
批准号:7726285
-
项目类别:
-
资助金额:$15.26万
-
财政年份:2008
-
负责人:ROBERT M SWEET
-
依托单位:
SOFTWARE DEVELOPMENT FOR EXPERIMENT CONTROL
-
批准号:7726282
-
项目类别:
-
资助金额:$45.79万
-
财政年份:2008
-
负责人:ROBERT M SWEET
-
依托单位:
MACROMOLECULAR STRUCTURE DETERMINATION - GENERAL USERS
-
批准号:7726267
-
项目类别:
-
资助金额:$62.15万
-
财政年份:2008
-
负责人:ROBERT M SWEET
-
依托单位:
国内基金
海外基金
登录
查看更多内容
具有抗癌活性的天然产物金霉酸(Aureolic acids)全合成与选择性构建2-脱氧糖苷键
-
批准号:22007039
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:王黎明
-
依托单位:
海洋放线菌来源聚酮类化合物Pteridic acids生物合成机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2019
-
负责人:朱义广
-
依托单位:
手性Lewis Acids催化的分子内串联1,5-氢迁移/环合反应及其在构建结构多样性手性含氮杂环化合物中的应用
-
批准号:21372217
-
项目类别:面上项目
-
资助金额:80.0万元
-
批准年份:2013
-
负责人:袁伟成
-
依托单位:
对空气稳定的新型的有机金属Lewis Acids催化剂制备、表征与应用研究
-
批准号:21172061
-
项目类别:面上项目
-
资助金额:30.0万元
-
批准年份:2011
-
负责人:许新华
-
依托单位:
钛及含钛Lewis acids促臭氧/过氧化氢体系氧化性能的广普性、高效性及其机制
-
批准号:21176225
-
项目类别:面上项目
-
资助金额:60.0万元
-
批准年份:2011
-
负责人:童少平
-
依托单位:
基于Zip Nucleic Acids引物对高度降解和低拷贝DNA检材的STR分型研究
-
批准号:81072511
-
项目类别:面上项目
-
资助金额:31.0万元
-
批准年份:2010
-
负责人:严江伟
-
依托单位:
海洋天然产物Makaluvic acids 的全合成及其对南海鱼虱存活的影响
-
批准号:30660215
-
项目类别:地区科学基金项目
-
资助金额:21.0万元
-
批准年份:2006
-
负责人:王世范
-
依托单位: