LIFE Study

生命研究

• 批准号: 8332543
• 负责人: Kurunthachalam Kannan
• 金额: $ 34.87万
• 依托单位: WADSWORTH CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-21 至 2012-12-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8332543
• 关键词: Adipose tissue; Biological Assay; Blood; Child; Clinical Trials; Contractor; Electronics; Endocrine disruption; Environment; Epidemiology; Fertility; Follicular Fluid; Future; Health; Individual; Investigation; Laboratory Procedures; National Institute of Child Health and Human Development; Parabens; Pathway interactions; Performance; Phenols; Phytoestrogens; Polychlorinated Biphenyls; Prevention Research; Process; Reporting; Research; Resources; Sampling; Seminal fluid; Services; Specimen; Specimen Handling; Urine; Woman; bisphenol A; environmental chemical; interest; men; phenyl ether; phthalates; research study; statistics

The contractor will provide the chemical environmental assay analysis services for the NICHD¿s Division of Epidemiology, Statistics and Prevention Research for the Longitudinal Investigation of Fertility and the Environment (LIFE) study of the analyses collected during the performance of the LIFE clinical trial. The contractor will provide analyses, of banked biospecimens, for NICHD¿s Division of Epidemiology, Statistics and Prevention Research studies of a spectrum of health effects in men, women and children that rely upon quantification of concentrations in de-identified biologic specimens, such as blood, urine, adipose tissue, follicular or seminal fluids. A variety of banked specimens will be analyzed for individual concentrations of both persistent and non-persistent environmental chemicals including those compounds that may disrupt endocrine pathways

承包商将为NICHD的流行病学、统计和预防研究部门提供化学环境测定分析服务，用于生育力和环境纵向调查（LIFE）研究，分析LIFE临床试验期间收集的分析。 承包商将为NICHD的流行病学、统计和预防研究司提供库存生物样本的分析，研究对男性、女性和儿童的一系列健康影响，这些研究依赖于对血液、尿液、脂肪组织、卵泡或精液等去识别生物样本中的浓度进行量化。将分析各种库存标本中持久性和非持久性环境化学品的个体浓度，包括可能干扰内分泌途径的化合物