NMR AND BIOCHEMICAL STUDIES OF BRAZZEIN WITH T1R2/T1R3 HETERORECEPTORS

具有 T1R2/T1R3 异受体的钎焊剂的核磁共振和生化研究

• 批准号: 8361253
• 负责人: FARIBA M ASSADI-PORTER
• 金额: $ 2.43万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361253
• 关键词: Biochemical; Biological; Fruit; Funding; Grant; National Center for Research Resources; Plants; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Source; South American; Structure; United States National Institutes of Health; cost; insight; mutant; receptor; sweet receptor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Brazzein is a sweet protein found in South American fruit plant Pentadiplatra brazzeana Baillon. The protein intereacts with the sweet repector T1R2-T1R3. To understand their biological significance and interaction with the sweet receptor, we need to understand the structures of sweet brazzein and the non-sweet mutants. This gives insight into their function and help understand interaction with the receptor.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 Brazzein是一种在南美水果植物五角星Brazzeana Baillon中发现的甜蛋白。蛋白质与甜repetor T1R2-T1R3相互作用。为了了解它们的生物学意义和与甜受体的相互作用，我们需要了解甜brazzein和非甜菜突变体的结构。这可以深入了解它们的功能并帮助了解与受体的相互作用。