ODT MONITORING INTRATUMORAL BLOOD FLOW DURING PHOTODYNAMIC THERAPY(PDT)

ODT 监测光动力治疗 (PDT) 期间的瘤内血流

• 批准号: 8362597
• 负责人: ZHONGPING CHEN
• 金额: $ 0.31万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362597
• 关键词: Biotechnology; Blood flow; Data; Diagnosis; Dose; Funding; Grant; Histologic; Human; Lasers; Light; Monitor; National Center for Research Resources; Photochemotherapy; Photosensitizing Agents; Principal Investigator; Research; Research Infrastructure; Resources; Skin Cancer; Source; Time; Tissues; United States National Institutes of Health; clinically significant; cost; light effects

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objectives of the proposed research will be two-fold (1) obtain data on the ability of ODT as a means of diagnosis of human skin cancer, as compared to conventional histologic examination; and (2) monitor intratumoral blood flow in real-time during Photodynamic Therapy (PDT). The administration of a sufficient dose of light, at the appropriate wavelength, to photosensitizer-containing tissue is essential for PDT. Accordingly, monitoring the effects of light delivery in tissue during PDT has great clinical significance.

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