SOFTWARE DISTRIBUTED BY THE NOBLE LAB, 2010-2011

NOBLE LAB 分发的软件，2010-2011 年

• 批准号: 8365904
• 负责人: William Noble
• 金额: $ 0.99万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365904
• 关键词: Biology; Complex Mixtures; Computer software; Databases; Funding; Fungal Genome; Grant; Mass Spectrum Analysis; Modeling; National Center for Research Resources; Peptides; Principal Investigator; Probability; Process; Proteins; Proteomics; Research; Research Infrastructure; Resources; Shotguns; Source; United States National Institutes of Health; base; cost; programs; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. # BiblioSpec enables the identification of peptides from tandem mass spectra by searching against a database of previously identified spectra. # Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. # Crux analyzes shotgun proteomics tandem mass spectra, associating peptides with observed spectra. # qvality performs nonparametric estimation of posterior error probabilities. # Fido uses a probability model to rank proteins according to the posterior probability of their presence in a complex mixture, based on evidence derived from a shotgun proteomics experiment.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 # BiblioSpec能够从串联质谱中识别肽 通过对先前识别的数据库进行搜索， 谱 # Percolator后处理鸟枪蛋白质组学的结果 数据库搜索程序，重新排序肽谱匹配， 列表的顶部被充实以用于正确的匹配。 # Crux分析鸟枪蛋白质组学串联质谱， 具有观察到的光谱的肽。 # qvality执行后验误差的非参数估计 概率 # Fido使用概率模型根据蛋白质的 它们在复杂混合物中存在的后验概率，基于 来自鸟枪蛋白质组学实验的证据。