SOFTWARE DISTRIBUTED BY THE NOBLE LAB, 2010-2011

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 #BiblioSpec允许从串联质量中识别多肽 通过在先前识别的数据库中搜索光谱 光谱。 #Percolator对鸟枪式蛋白质组学的结果进行后处理 数据库搜索程序，对肽谱匹配进行重新排序，以便 列表的顶部更加丰富，以实现正确的匹配。 #Crux分析猎枪蛋白质组学串联质谱图，将 观察到光谱的多肽。 #qvality执行后验误差的非参数估计 概率。 #FIDO使用概率模型根据 它们存在于复杂混合物中的后验概率，基于 来自一项猎枪蛋白质组学实验的证据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. # BiblioSpec enables the identification of peptides from tandem mass spectra by searching against a database of previously identified spectra. # Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. # Crux analyzes shotgun proteomics tandem mass spectra, associating peptides with observed spectra. # qvality performs nonparametric estimation of posterior error probabilities. # Fido uses a probability model to rank proteins according to the posterior probability of their presence in a complex mixture, based on evidence derived from a shotgun proteomics experiment.