Infectious Diseases Training Program

传染病培训计划

• 批准号: 8338320
• 负责人: BETH C LEVINE
• 金额: $ 12.33万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8338320
• 关键词: Communicable Diseases; Training Programs

DESCRIPTION (provided by applicant): Infectious diseases continue to represent the most important global health threat to mankind; yet inadequate numbers of physician-scientists are being trained who are prepared for academic research careers that can impact our understanding of the pathogenesis and treatment of infectious diseases. We propose the continuation of the UT Southwestern (UTSW) Infectious Diseases postdoctoral training program to train physician-scientists to perform cutting edge basic science research related to host-pathogen interactions. This program provides training for Adult and Pediatric Infectious Diseases Fellows (as well as Pulmonary and Digestive and Liver Fellows who are interested in host-pathogen interactions). The overall goal of this program is to train physician-scientists for successful careers in academic infectious diseases-related research. Specific goals of the research training are for trainees to: (1) develop proficiency in state-of-the art- techniques relevant to infectious diseases research in the area of host-pathogen interactions; (2) gain expertise in a relevant area of biomedical science, such a microbial genetics, immunology, cell biology, biochemistry, or pharmacology; (3) gain expertise and independence in generating strong research hypotheses and in rigorous experimental design and data interpretation; and (4) complete a mentored research project that leads to one or more first-authored peer reviewed publications and NIH career development award applications. These goals will be accomplished by a combination of (1) intensive supervised basic science research experience in the laboratories of our 22 program training faculty (all of whom are outstanding NIH-funded scientists performing exciting work in the field of host-pathogen interactions); (2) a comprehensive didactic curriculum that includes required courses and electives in biomedical sciences, ethics, statistics, and career development; (3) active mentoring and career development by the primary mentor and thesis committee members; and (4) the opportunity to train in a highly interactive and stimulating interdisciplinary scientific environment. This comprehensive and multi-faceted approach will result in the training of post-doctoral fellows in Infectious Diseases research with strong potential to succeed in academic research careers and strong potential to perform basic science research that will impact the prevention and/or treatment of infectious diseases. PUBLIC HEALTH RELEVANCE: The goal of the UT Southwestern Infectious Diseases Training Program is to provide Adult and Pediatric Infectious Diseases Fellows (and other clinical fellows with a research interest in Infectious Diseases) with in-depth research training i the area of the biology of pathogens and host-pathogen interactions. This training will prepare them for careers as physician scientists in academic medicine and enable them to discover new knowledge that will advance our understanding of the causes and treatment of infectious diseases. To achieve this goal, the program provides an intensive 2-3 year experience in basic science research supplemented by formal didactic instruction in biomedical sciences, career development, and ethics.

描述（由申请人提供）：传染病仍然是对人类最重要的全球健康威胁；然而，正在接受培训、为学术研究生涯做好准备的医师科学家数量不足，而学术研究生涯可能会影响我们对传染病发病机制和治疗的理解。我们建议继续开展德州大学西南分校 (UTSW) 传染病博士后培训计划，以培训医师科学家开展与宿主-病原体相互作用相关的前沿基础科学研究。该计划为成人和儿童传染病研究员（以及对宿主与病原体相互作用感兴趣的肺、消化和肝脏研究员）提供培训。该计划的总体目标是培训医师科学家，使其在学术传染病相关研究中取得成功的职业生涯。研究培训的具体目标是让学员：（1）熟练掌握与宿主-病原体相互作用领域的传染病研究相关的最先进技术； (2) 获得生物医学科学相关领域的专业知识，例如微生物遗传学、免疫学、细胞生物学、生物化学或药理学； (3) 在产生强有力的研究假设以及严格的实验设计和数据解释方面获得专业知识和独立性； (4) 完成一个指导研究项目，该项目将导致一篇或多篇第一作者的同行评审出版物和 NIH 职业发展奖申请。这些目标将通过以下方面的结合来实现：(1) 我们 22 名项目培训教师实验室中的强化监督基础科学研究经验（他们都是 NIH 资助的杰出科学家，在宿主与病原体相互作用领域开展了令人兴奋的工作）； (2) 全面的教学课程，包括生物医学、伦理学、统计学和职业发展方面的必修课和选修课； （3）主要导师和论文委员会成员的积极指导和职业发展； (4) 在高度互动和刺激的跨学科科学环境中接受培训的机会。这种全面、多方面的方法将培训传染病研究领域的博士后研究员，他们具有在学术研究生涯中取得成功的巨大潜力，以及进行影响传染病预防和/或治疗的基础科学研究的巨大潜力。 公共卫生相关性：德州大学西南传染病培训计划的目标是为成人和儿童传染病研究员（以及其他对传染病研究感兴趣的临床研究员）提供病原体生物学和宿主-病原体相互作用领域的深入研究培训。这项培训将为他们成为学术医学领域的医师科学家做好准备，并使他们能够发现新知识，从而增进我们对传染病病因和治疗的理解。为了实现这一目标，该项目提供 2-3 年的基础科学研究强化经验，并辅以生物医学科学、职业发展和伦理学方面的正式教学指导。