Core E - Outreach, Recruitment and Education Core

核心 E - 外展、招聘和教育核心

• 批准号: 8676354
• 负责人: REISA A. SPERLING
• 金额: $ 16.1万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8676354
• 关键词: Alzheimer' s Disease; Amyloid; Area; Awareness; Biological Markers; Boston; Clinic; Clinical; Clinical Research; Clinical Trials; Commit; Communities; Community Health; Community Health Education; Community Outreach; Dementia; Disease; Early Diagnosis; Early Intervention; Early intervention trials; Education; Enrollment; Evolution; Fellowship; Funding; Health Professional; Human Resources; Image; Imaging Techniques; Impaired cognition; Individual; Industry; Institutes; Language; Lead; Leadership; Massachusetts; Memory; Methods; Metric; Mission; Needs Assessment; Neurodegenerative Disorders; Observational Study; Participant; Patients; Pilot Projects; Population; Positron-Emission Tomography; Prevention; Public Health; Questionnaires; Recruitment Activity; Registries; Research; Research Design; Research Personnel; Research Project Grants; Risk; Secondary Prevention; Staging; Symptoms; Training; Training Programs; Underrepresented Minority; United States National Institutes of Health; Work; Writing; abstracting; amyloid imaging; base; career development; cohort; experience; imaging modality; improved; innovation; interest; meetings; neuroimaging; outreach; pre-clinical; programs; public education; racial and ethnic; research study; satisfaction; socioeconomics; volunteer

OUTREACH, RECRUITMENT & EDUCATION CORE PROJECT SUMMARY/ABSTRACT The MADRC Outreach, Recruitment, and Education Core has transitioned to new leadership over the past two years and has refocused its mission on community outreach and facilitating rapid enrollment into MADRC affiliated clinical research studies. The evolution of our field towards earlier detection and intervention in AD presents new challenges for public education and for recruitment of diverse participants into biomarker intensive studies. We seek to provide leadership in increasing public awareness about the critical importance of participation in AD clinical research and develop accessible information on the evolving concepts of very early AD. Over the past cycle, we supported the highly successful recruitment and retention of subjects for the Longitudinal Cohort as well as multiple MADRC affiliated clinical research projects and national multi-center studies, including ADNI, DIAN, ADCS and industry sponsored clinical trials. We have now instituted a proactive needs assessment for the Longitudinal Cohort (LC) and to support new MADRC affiliated research and national multi-center projects. We are working closely with the Clinical Core on retention of the Longitudinal Cohort, particularly participants from under-represented minorities, and to build a comprehensive Research Registry to supplement the LC in identifying clinically normal individuals and symptomatic patients who are ready to enroll in clinical research projects. We propose several new programs to serve the diversity recruitment needs of our Center, including an innovative Participant Ambassador Program and partnership with the Clinical Core on the new Spanish Memory Clinic. We are expanding our outreach to local community health and senior centers to increase the diversity of research participants. We are also reinvigorating our partnership with a diverse Community Advisory Board to better understand the potential barriers to enrolling participants from under-represented minority communities into intensive clinical trials with biomarker and imaging procedures, such as the ADCS Anti-Amyloid Treatment in Asymptomatic AD (A4) secondary prevention trial. We will coordinate with the newly proposed Neuroimaging Core, and our colleagues at other ADCs, to develop informative materials to educate the public and professionals about the appropriate use of PET amyloid imaging and methods to safely disclose information about amyloid status to research participants. We will implement quantitative metrics to assess our impact in community education programs and will develop anonymous subject satisfaction questionnaires to further improve the experience of our research participants. We remain committed to training young investigators and clinicians about the importance of early detection of AD and related dementias, and will support educational forums focused on advances in AD research, both locally and nationally, as well as working with the educational components of each of the MADRC cores to enhance training programs across the Center.

外展、再培训和教育核心项目概要/摘要 过去两年，MADRC外展、招聘和教育核心已过渡到新的领导层 多年来，它重新将其使命的重点放在社区外展和促进快速注册到MADRC 附属临床研究。我们的领域朝着早期发现和干预AD的方向发展 为公众教育和招募不同参与者进入生物标志物密集型提出了新的挑战 问题研究我们力求发挥领导作用，提高公众对以下问题的重要性的认识： 参与AD临床研究，并开发有关早期发展概念的可访问信息 AD.在过去的一个周期里，我们支持了非常成功的招募和保留受试者， 纵向队列以及多个MADRC附属临床研究项目和国家多中心 研究，包括ADNI、DIAN、ADCS和行业赞助的临床试验。我们现在已经建立了一个积极的 纵向队列（LC）的需求评估，并支持新的MADRC附属研究和国家 多中心项目。我们正在与临床核心密切合作，以保留纵向队列， 特别是来自代表性不足的少数民族的参与者，并建立一个全面的研究登记处， 补充LC以识别准备入组的临床正常个体和有症状患者 临床研究项目。我们提出了几个新的计划，以满足我们的多元化招聘需求 中心，包括创新的参与者大使计划和与临床核心的合作伙伴关系， 新的西班牙记忆诊所我们正在扩大对当地社区卫生和老年中心的服务， 增加研究参与者的多样性。我们也正在重振我们的伙伴关系， 社区咨询委员会，以更好地了解潜在的障碍，以招募参与者从 代表性不足的少数民族社区进入密集的临床试验与生物标志物和成像程序， 例如ADCS抗淀粉样蛋白治疗无症状AD（A4）二级预防试验。我们将 与新提出的神经成像核心和我们在其他ADC的同事协调， 教育公众和专业人员正确使用PET淀粉样蛋白成像的信息材料 以及向研究参与者安全地披露关于淀粉样蛋白状态的信息的方法。落实 量化指标，以评估我们在社区教育计划的影响，并将开发匿名 受试者满意度调查问卷，以进一步改善我们的研究参与者的经验。我们仍然 致力于培训年轻的研究人员和临床医生关于早期发现AD的重要性， 相关痴呆症，并将支持教育论坛，重点是在AD研究的进展，无论是在当地和 在全国范围内，以及与每个MADRC核心的教育部门合作，以加强培训 整个中心的方案。