Core E - Outreach, Recruitment and Education Core

外展、招聘和教育核心项目摘要/摘要 在过去的两年中，MADRC的推广、招聘和教育核心已经过渡到新的领导层 多年来，并将其使命重新集中在社区外联和促进快速加入MADRC 附属临床研究。我们的领域朝着AD早期检测和干预的方向发展 对公共教育和招募不同参与者进入生物标志物密集型提出了新的挑战 学习。我们力求发挥领导作用，提高公众对以下问题的认识 参与AD临床研究，并开发关于很早就不断演变的概念的可访问信息 广告。在过去的一个周期中，我们支持非常成功地招聘和保留 纵向队列以及多个MADRC附属临床研究项目和国家多中心 研究，包括ADNI、DIAN、ADCS和行业赞助的临床试验。我们现在已经建立了一个积极主动的 对纵向队列(LC)的需求评估，并支持新的MADRC附属研究和国家 多中心项目。我们正在与临床核心密切合作，以保留纵向队列， 特别是来自代表性不足的少数群体的参与者，并建立一个全面的研究登记处，以 补充LC以确定准备登记的临床正常个体和有症状的患者 在临床研究项目中。我们提出了几个新的计划，以满足我们的多元化招聘需求 中心，包括创新参与者大使计划和与临床核心的合作伙伴关系 新的西班牙语记忆诊所。我们正在将我们的外展范围扩大到当地社区卫生和老年中心，以 增加研究参与者的多样性。我们还在通过一个多样化的 社区咨询委员会，以更好地了解注册参与者的潜在障碍 利用生物标记物和成像程序进行密集的临床试验， 例如无症状AD(A4)二级预防试验中的ADCS抗淀粉样蛋白治疗。我们会 与新提出的神经成像核心以及我们在其他ADC的同事协调，以开发 教育公众和专业人员正确使用PET淀粉样成像的信息材料 以及向研究参与者安全地披露淀粉样蛋白状态信息的方法。我们将实施 评估我们在社区教育项目中的影响的量化指标，并将开发匿名 研究对象满意度问卷，以进一步改善我们研究参与者的体验。我们会留下来 致力于培训年轻的研究人员和临床医生，使他们了解早期发现AD和 并将支持侧重于AD研究进展的教育论坛，包括当地和 在全国范围内，并与每个MADRC核心的教育部门合作，以加强培训 整个中心的计划。

OUTREACH, RECRUITMENT & EDUCATION CORE PROJECT SUMMARY/ABSTRACT The MADRC Outreach, Recruitment, and Education Core has transitioned to new leadership over the past two years and has refocused its mission on community outreach and facilitating rapid enrollment into MADRC affiliated clinical research studies. The evolution of our field towards earlier detection and intervention in AD presents new challenges for public education and for recruitment of diverse participants into biomarker intensive studies. We seek to provide leadership in increasing public awareness about the critical importance of participation in AD clinical research and develop accessible information on the evolving concepts of very early AD. Over the past cycle, we supported the highly successful recruitment and retention of subjects for the Longitudinal Cohort as well as multiple MADRC affiliated clinical research projects and national multi-center studies, including ADNI, DIAN, ADCS and industry sponsored clinical trials. We have now instituted a proactive needs assessment for the Longitudinal Cohort (LC) and to support new MADRC affiliated research and national multi-center projects. We are working closely with the Clinical Core on retention of the Longitudinal Cohort, particularly participants from under-represented minorities, and to build a comprehensive Research Registry to supplement the LC in identifying clinically normal individuals and symptomatic patients who are ready to enroll in clinical research projects. We propose several new programs to serve the diversity recruitment needs of our Center, including an innovative Participant Ambassador Program and partnership with the Clinical Core on the new Spanish Memory Clinic. We are expanding our outreach to local community health and senior centers to increase the diversity of research participants. We are also reinvigorating our partnership with a diverse Community Advisory Board to better understand the potential barriers to enrolling participants from under-represented minority communities into intensive clinical trials with biomarker and imaging procedures, such as the ADCS Anti-Amyloid Treatment in Asymptomatic AD (A4) secondary prevention trial. We will coordinate with the newly proposed Neuroimaging Core, and our colleagues at other ADCs, to develop informative materials to educate the public and professionals about the appropriate use of PET amyloid imaging and methods to safely disclose information about amyloid status to research participants. We will implement quantitative metrics to assess our impact in community education programs and will develop anonymous subject satisfaction questionnaires to further improve the experience of our research participants. We remain committed to training young investigators and clinicians about the importance of early detection of AD and related dementias, and will support educational forums focused on advances in AD research, both locally and nationally, as well as working with the educational components of each of the MADRC cores to enhance training programs across the Center.