Immunology Training Program - Predoctoral

描述(由申请人提供)：免疫学培训计划(ITP)的目标是为免疫学相关研究领域的杰出职业培养博士和医学/博士科学家。该计划包括广泛的免疫学相关主题，从先天免疫、T细胞激活、耐受性、抗原处理和呈递、MHC功能、补体、抗体结构和功能以及粘膜免疫等领域的基础研究，到临床相关传染病模型(如结核病、艾滋病毒)、疫苗开发、免疫病理学、移植和自身免疫的研究。参与部门提供丰富的基础科学和临床活动和资源，丰富了对从事免疫学领域基础和/或转化性研究的博士生的培训。为了实现这些培训目标，ITP已被开发为病理学研究生计划中的一个轨道。ITP的博士学位培训包括课程工作、研究轮换、正式和非正式研讨会、论文提案答辩/资格考试，以及撰写学术出版物和博士论文的研究经验。培训人员和研究实验室设在凯斯医学院及其附属机构的多个系中。大学医院案例医学中心(UHCMC)、克利夫兰临床基金会(CCF，包括勒纳研究所)和路易斯斯托克斯退伍军人医学中心(VAMC)。CWRU病理学系、CCF免疫学系、CWRU/UHCMC传染病部门、CWRU全球卫生中心和CWRU/UHCMC视觉科学研究中心明确共同赞助了ITP，突显了部门间和机构间的广泛参与。在CASE、CCF、UHCMC、MHMC和VAMC的许多其他部门设有其他ITP培训员。无论他们的主要从属关系如何，ITP培训师都会在病理学系担任教员或培训师。 相关性：免疫学培训计划提供博士培训，以培养未来的研究人员，他们将推动免疫学和免疫学相关临床重要领域的重要生物医学研究工作，如传染病、疫苗开发和器官移植自身免疫。

DESCRIPTION (provided by applicant): The goal of the Immunology Training Program (ITP) is to train PhD and MD/PhD scientists for outstanding careers in immunology-related research. The program includes a wide range of Immunology-related topics, spanning from basic research in areas such as innate immunity, T cell activation, tolerance, antigen processing and presentation, MHC function, complement, antibody structure and function, and mucosal immunity to research in clinically relevant models of infectious diseases (e.g. tuberculosis, HIV), vaccine development, immunopathology, transplantation and autoimmunity. Participating departments provide a rich confluence of basic science and clinical activities and resources, enriching the training of PhD students as they engage in basic and/or translational research in the field of immunology. To accomplish these training goals, the ITP has been developed as a track within the Pathology Graduate Program. Training for the PhD degree in the ITP includes course work, research rotations, formal and informal seminars, a Thesis Proposal Defense/Qualifying Examination, and research experience resulting in scholarly publications and a PhD dissertation. Trainers and research laboratories are located in multiple departments at Case School of Medicine and its affiliated institutions. University Hospitals Case Medical Center (UHCMC), the Cleveland Clinic Foundation (CCF, including the Lerner Research Institute) and the Louis Stokes VA Medical Center (VAMC). The extensive inter-departmental and inter-institutional participation is underscored by explicit co-sponsorship of the ITP by the CWRU Department of Pathology, CCF Department of Immunology, CWRU/UHCMC Division of Infectious Diseases, CWRU Center for Global Health and CWRU/UHCMC Visual Sciences Research Center. Other ITP trainers are located in a wide number of other departments at Case, CCF, UHCMC, MHMC and VAMC. Regardless of their primary affiliation, ITP Trainers hold faculty or trainer appointments in the Case Department of Pathology. RELEVANCE: The Immunology Training Program provides PhD training to produce future investigators who will drive important biomedical research efforts in Immunology and Immunology-related areas of clinical importance, such as infectious diseases, vaccine development, and organ transplantation autoimmunity.