Immunology Training Program-Predoctoral

项目摘要 凯斯西储大学(CWRU)医学院(SOM)是免疫学研究的领先者 和教育，几十年来对该领域做出开创性贡献的丰富历史，包括 补体的替代途径。免疫学培训计划领导轨道(ITP-LT)是 更广泛的免疫学博士计划内的培训计划，旨在利用众多 该机构及其附属机构的优势，包括CWRU SOM，University的多个部门 医院克利夫兰医疗中心(UHCMC)、克利夫兰诊所基金会(CCF；包括勒纳 )和路易斯斯托克斯退伍军人医学中心(VAMC)，培养博士和医学/博士科学家 在免疫学相关研究方面的杰出职业。领导力的发展道路特别强调 为学术界和工业界培养下一代调查小组组长(制药和 生物技术)作为中心目标。参与式导师提供了丰富的基础科学、临床 活动和资源，以及职业发展研讨会，以丰富对博士生的培训 从事基础和/或翻译研究，范围从先天免疫和信号、T细胞生物学、抗原 加工呈递、补体、抗体结构与功能、粘膜免疫等方面的研究 在临床相关的传染病模型(如结核病、艾滋病毒、疟疾)中，免疫病理学， 移植和自身免疫。此外，CWRU SOM有一个新开发的系统中心 免疫学(CSI)，并在糖免疫学方面建立了罕见的强项声誉，或者说多糖和 它们在免疫反应中的结合伙伴。ITP-LT利用了这些优势，并享受了显式 由CWRU病理科、CCF炎症免疫部联合主办， CWRU/UHCMC传染病司和CWRU全球卫生和疾病中心。这些 独特的研究机会对ITP-LT目前和未来的成功至关重要。博士生培训 该项目的学位包括课程作业、研究轮换、正式和非正式研讨会、论文提案。 国防/资格考试，学术出版物的研究经验，职业发展 活动、博士论文和各种机会汇聚一堂，分享和庆祝 该计划的不同受训人口取得的成就。

Project Summary The Case Western Reserve University (CWRU) School of Medicine (SOM) is a leader in immunology research and education, with a rich history of seminal contributions to the field over many decades, including the discovery of the alternative pathway of complement. The Immunology Training Program Leadership Track (ITP-LT) is a training program within the broader Immunology PhD Program that is built to capitalize on the numerous strengths of the institution and our affiliates, which includes multiple departments at CWRU SOM, University Hospitals Cleveland Medical Center (UHCMC), the Cleveland Clinic Foundation (CCF; including the Lerner Research Institute) and the Louis Stokes VA Medical Center (VAMC), to prepare PhD and MD/PhD scientists for outstanding careers in immunology-related research. The Leadership Track places extra emphasis on developing the next generation of investigative group leaders for academia and industry (pharmaceuticals and biotechnology) as a central goal. Participating mentors provide a rich confluence of basic science, clinical activities and resources, and career development workshops to enrich the training of PhD students as they engage in basic and/or translational research ranging from innate immunity and signaling, T cell biology, antigen processing and presentation, complement, antibody structure and function, and mucosal immunity to research in clinically relevant models of infectious diseases (e.g. tuberculosis, HIV, malaria), immunopathology, transplantation and autoimmunity. Moreover, CWRU SOM has a newly developed Center for Systems Immunology (CSI) and has built a rare reputation for strength in glycoimmunology, or the role of glycans and their binding partners in the immune response. The ITP-LT draws upon these strengths and enjoys the explicit co-sponsorship by the CWRU Department of Pathology, CCF Department of Inflammation and Immunity, CWRU/UHCMC Division of Infectious Diseases, and the CWRU Center for Global Health and Disease. These unique research opportunities are central to the ongoing and future success of the ITP-LT. Training for the PhD degree in the program includes course work, research rotations, formal and informal seminars, a Thesis Proposal Defense/Qualifying Examination, research experience resulting in scholarly publications, career development activities, a PhD dissertation, and a variety of opportunities to come together to share and celebrate the accomplishments of the program's diverse population of trainees.