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toxic and carcinogenic potential of alpha-pinene in laboratory animals for the National Toxicology Program (NTP)

toxic and carcinogenic potential of alpha-pinene in laboratory animals for the National Toxicology Program (NTP)
国家毒理学计划 (NTP) 的实验动物中 α-蒎烯的毒性和致癌潜力
批准号：
8948077
负责人：
MILTON D HEJTMANCIK
金额：
$107.83万
依托单位：
BATTELLE MEMORIAL INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
项目状态：
已结题
起止时间：
2014-04-15 至 2015-04-14
来源：
https://reporter.nih.gov/project-details/8948077
关键词：
AnimalsBreathingChemicalsChemistryChronicEngineeringFertilityFlavoringGoalsHumanInhalation ExposureLaboratory AnimalsMusNational Toxicology ProgramPhaseProcessRattusSelf CareSperm Count ProcedureSperm MotilitySystemToxic effectToxicity TestsTurpentinealpha-pinenecarcinogenicityhazardmalereproductive

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中文摘要
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英文摘要
The goal of this project is to evaluate the chronic toxicity and carcinogenicity of alpha-pinene in rats and mice, following whole body inhalation exposure. Alpha-pinene is found in turpentine and in flavorings and fragrances. Humans may be exposed through use of personal care and cleaning products as well as in lumber processing and building activities. 2-Year chronic toxicity and carcinogenicity studies of alpha-pinene are in the chemistry and inhalation exposure system engineering phase phase. These studies include an assessment of fertility and sperm count and motility, as male reproductive effects are anticipated. Keywords: toxicity, carcinogenicity, inhalation, alpha-pinene
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