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Conduct of studies to evaluate the toxic and carcinogenic potential of naturally occurring asbestos in laboratory animals for the National Toxicology Program (NTP)

Conduct of studies to evaluate the toxic and carcinogenic potential of naturally occurring asbestos in laboratory animals for the National Toxicology Program (NTP)
为国家毒理学计划 (NTP) 开展研究,评估实验动物中天然存在的石棉的毒性和致癌潜力
批准号:
9162302
负责人:
MILTON D HEJTMANCIK
金额:
$100.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-04-15 至 2015-04-14

项目摘要

项目成果

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中文摘要
翻译
本项目的目标是发展吸入暴露和组织负荷制备和分析方法,以促进NTPs设计天然石棉的毒性和致癌性研究。有必要就不同类型的石棉纤维产生高质量的剂量反应数据。然而,在完成这些研究的设计之前,有许多方法上的挑战需要解决。方法开发工作目前正在进行中。
英文摘要
The goal of this project is to develop inhalation exposure and tissue burden preparation and analysis methods to facilitate the NTPs designing of toxicity and carcinogenicity studies of naturally occurring asbestos. There is a need to generate high quality, dose response data on different types of asbestos fibers. However, there are numerous methodological challenges that need to be resolved prior to finalization of the design of these studies. Method development work is currently in progress. Keywords: toxicity, carcinogenicity, asbestos, inhalation, fiber
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Conduct of studies to evaluate the toxic and carcinogenic potential of sulfolane in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    9162301
  • 项目类别:
  • 资助金额:
    $252.62万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
toxic and potential of vanadyl sulfate and sodium metavanadate in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    8948076
  • 项目类别:
  • 资助金额:
    $81.42万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
Conduct of studies to evaluate the toxic and potential of vanadyl sulfate and sodium metavanadate in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    9162299
  • 项目类别:
  • 资助金额:
    $100.0万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
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toxic and carcinogenic potential of alpha-pinene in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    8948077
  • 项目类别:
  • 资助金额:
    $107.83万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
海外基金