Johns Hopkins Adolescent Medicine Trials Unit

约翰霍普金斯大学青少年医学试验中心

• 批准号: 8834839
• 负责人: ALLISON L AGWU
• 金额: $ 26.9万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8834839
• 关键词: AIDS/HIV problem; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Adolescent and Young Adult; Affect; Baltimore; Child; Child health care; Childhood; Cities; Clinical; Collaborations; Communities; Community Health; Diagnosis; HIV; HIV Seropositivity; Health; IMPAACT; Institution; Intervention; Life; Medical; Pediatrics; Physician Executives; Prevention program; Principal Investigator; Qualifying; Recruitment Activity; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Risk; Site; Social Work; Syphilis; Universities; Work; Youth; aged; base; design; experience; forging; innovation; medical schools; outreach; pediatric department; professor; programs; psychosocial; success; treatment program; young adult

DESCRIPTION (provided by applicant): As of December 31, 2008, there were 252 children and adolescents aged 0-19 and 917 young adults aged 20- 29 with a reported HIV/AIDS diagnosis living in the city of Baltimore. The Pediatric and Adolescent HIV/AIDS Program (PAHAP) in the Johns Hopkins Children's Center in collaboration with its Center for Child and Community Health Research (CCHR) and the Adolescent Medicine Program is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The PAHAP offers comprehensive medical, psychosocial, outreach and social services to HIV-positive, HIV-affected, and at-risk adolescents in the context of a large, productive research institution located in East Baltimore City. The proposed Principal Investigator of the Johns Hopkins AMTU, Dr. Jonathan Ellen, is Professor and Vice Chair in the Department of Pediatrics at the Johns Hopkins University School of Medicine and is board certified in Pediatrics and Adolescent Medicine. He is Principal Investigator on the IMPAACT CTU site at Johns Hopkins and he co-directs PAHAP and the Adolescent Medicine Program. In addition to his work at these clinical programs, Dr. Ellen is Director of the CCHR. With his direction, the CCHR has designed and managed independent adolescent research projects and successfully participated in multi-site collaborative studies. The CCHR's infrastructure is responsible for many of the treatment and prevention programs provided in the PAHAP and the community. Further, in his capacity as Medical Director for the Baltimore City Health Department (HCHD) Syphilis Elimination Program, Dr. Ellen has forged a strong reciprocal relationship between the CCHR, PHAP and the BCHD that insures continued identification and referral of HIV-infected and at-risk adolescents and young adults to the PAHAP. Based on the combined expertise of the PAHAP and the CCHR, the use of innovative programs in reaching disenfranchised youth, demonstrated success in recruiting and retaining youth in trials, and productive collaborations with our community, we believe that the Johns Hopkins AMTU would offer significant operational and scientific contributions to the ATN agenda. RELEVANCE: The Pediatric and Adolescent HIV/AIDS Program (PAHAP) proposes to establish an Adolescent Medicine Trials Unit (ATU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The expertise of the investigators and experience of the staff make the PAHAP well qualified to be an effective ATU and contribute to the ATN.

描述(申请人提供)：截至2008年12月31日，巴尔的摩市有252名0-19岁的儿童和青少年和917名20-29岁的年轻人被诊断为艾滋病毒/艾滋病。约翰霍普金斯儿童中心的儿童和青少年艾滋病毒/艾滋病计划(PAHAP)与其儿童和社区健康研究中心(CCHR)以及青少年医学计划合作，正在申请成为青少年医学艾滋病毒/艾滋病干预试验网络(ATN)中的青少年医学试验单位(AMTU)。PAHAP在位于巴尔的摩市东部的一个大型研究机构的背景下，向艾滋病毒阳性、艾滋病毒感染和高危青少年提供全面的医疗、心理社会、外展和社会服务。约翰霍普金斯大学AMTU的拟议首席研究员乔纳森·艾伦博士是约翰·霍普金斯大学医学院儿科系的教授和副主席，并拥有儿科和青少年医学委员会证书。他是约翰·霍普金斯大学IMPAACT CTU网站的首席研究员，他是PAHAP和青少年医学计划的联合负责人。除了在这些临床项目上的工作外，Ellen博士还是CCHR的主任。在他的指导下，CCHR设计和管理了独立的青少年研究项目，并成功地参与了多地点合作研究。CCHR的基础设施负责PAHAP和社区提供的许多治疗和预防方案。此外，作为巴尔的摩市卫生局(HCHD)消除梅毒项目的医务主任，Ellen博士在CCHR、Phap和BCHD之间建立了牢固的互惠关系，以确保持续识别和转介感染艾滋病毒和高危青少年和年轻人到PAHAP。基于PAHAP和CCHR的综合专业知识，在帮助被剥夺公民权的青年方面使用创新计划，在试验中成功招募和留住青年，以及与我们社区的富有成效的合作，我们相信约翰霍普金斯大学AMTU将为ATN议程做出重大的业务和科学贡献。 相关性：儿童和青少年艾滋病毒/艾滋病方案(PAHAP)建议在青少年医学艾滋病毒/艾滋病干预试验网络(ATN)中设立一个青少年医学试验股(ATU)。调查人员的专业知识和工作人员的经验使PAHAP完全有资格成为一个有效的ATU，并为ATN做出贡献。