Johns Hopkins Adolescent Medicine Trials Unit

约翰霍普金斯大学青少年医学试验中心

• 批准号: 8834839
• 负责人: ALLISON L AGWU
• 金额: $ 26.9万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8834839
• 关键词: AIDS/HIV problem; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Adolescent and Young Adult; Affect; Baltimore; Child; Child health care; Childhood; Cities; Clinical; Collaborations; Communities; Community Health; Diagnosis; HIV; HIV Seropositivity; Health; IMPAACT; Institution; Intervention; Life; Medical; Pediatrics; Physician Executives; Prevention program; Principal Investigator; Qualifying; Recruitment Activity; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Risk; Site; Social Work; Syphilis; Universities; Work; Youth; aged; base; design; experience; forging; innovation; medical schools; outreach; pediatric department; professor; programs; psychosocial; success; treatment program; young adult

DESCRIPTION (provided by applicant): As of December 31, 2008, there were 252 children and adolescents aged 0-19 and 917 young adults aged 20- 29 with a reported HIV/AIDS diagnosis living in the city of Baltimore. The Pediatric and Adolescent HIV/AIDS Program (PAHAP) in the Johns Hopkins Children's Center in collaboration with its Center for Child and Community Health Research (CCHR) and the Adolescent Medicine Program is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The PAHAP offers comprehensive medical, psychosocial, outreach and social services to HIV-positive, HIV-affected, and at-risk adolescents in the context of a large, productive research institution located in East Baltimore City. The proposed Principal Investigator of the Johns Hopkins AMTU, Dr. Jonathan Ellen, is Professor and Vice Chair in the Department of Pediatrics at the Johns Hopkins University School of Medicine and is board certified in Pediatrics and Adolescent Medicine. He is Principal Investigator on the IMPAACT CTU site at Johns Hopkins and he co-directs PAHAP and the Adolescent Medicine Program. In addition to his work at these clinical programs, Dr. Ellen is Director of the CCHR. With his direction, the CCHR has designed and managed independent adolescent research projects and successfully participated in multi-site collaborative studies. The CCHR's infrastructure is responsible for many of the treatment and prevention programs provided in the PAHAP and the community. Further, in his capacity as Medical Director for the Baltimore City Health Department (HCHD) Syphilis Elimination Program, Dr. Ellen has forged a strong reciprocal relationship between the CCHR, PHAP and the BCHD that insures continued identification and referral of HIV-infected and at-risk adolescents and young adults to the PAHAP. Based on the combined expertise of the PAHAP and the CCHR, the use of innovative programs in reaching disenfranchised youth, demonstrated success in recruiting and retaining youth in trials, and productive collaborations with our community, we believe that the Johns Hopkins AMTU would offer significant operational and scientific contributions to the ATN agenda. RELEVANCE: The Pediatric and Adolescent HIV/AIDS Program (PAHAP) proposes to establish an Adolescent Medicine Trials Unit (ATU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The expertise of the investigators and experience of the staff make the PAHAP well qualified to be an effective ATU and contribute to the ATN.

描述（由申请人提供）：截至2008年12月31日，有252名年龄在0-19岁的儿童和青少年和917名20-29岁的年轻人，据报道，据报道，居住在巴尔的摩市的HIV/AIDS诊断。约翰·霍普金斯儿童中心的儿科和青少年艾滋病毒/艾滋病计划（PAHAP）与其儿童和社区健康研究中心（CCHR）和青少年医学计划合作，适用于青少年医学试验单位（AMTU），在青少年医学试验中，用于HIV/HIV/AIDS INDES INSESS INTERSENTIONS（ATN）。 PAHAP在位于东巴尔的摩市的大型生产研究机构的背景下，为艾滋病毒阳性，受艾滋病毒影响和高危青少年提供全面的医疗，心理社会，外展和社会服务。约翰·霍普金斯·安图（Johns Hopkins Amtu）的拟议首席研究员乔纳森·埃伦（Jonathan Ellen）博士是约翰·霍普金斯大学医学院儿科学系教授兼副主席，并获得儿科和青少年医学的董事会认证。他是约翰·霍普金斯（Johns Hopkins）不可行的CTU网站上的首席研究员，他与Pahap和青少年医学计划合作。除了在这些临床计划中的工作外，Ellen博士还是CCHR的主任。 CCHR凭借他的方向设计和管理独立的青少年研究项目，并成功地参与了多站点的协作研究。 CCHR的基础设施负责PAHAP和社区中提供的许多治疗和预防计划。此外，艾伦博士以担任巴尔的摩市卫生部（HCHD）梅毒消除计划的医疗总监，在CCHR，PHAP和BCHD之间建立了牢固的相互关系，以确保对HIV感染的HIV感染者和高危青少年和年轻人继续识别和转诊。根据PAHAP和CCHR的综合专业知识，使用创新计划在达到剥夺选举权的青年方面，在试验中招募和留住青年方面取得了成功，以及与我们的社区的富有成效的合作，我们相信Johns Hopkins Amtu将为ATN ATN议程提供重大的运营和科学贡献。 相关性：小儿和青少年艾滋病毒/艾滋病计划（PAHAP）提议在青少年医学艾滋病毒/艾滋病干预措施（ATN）中建立青少年医学试验单元（ATU）。调查人员的专业知识和工作人员的经验使Pahap有效地成为有效的ATU，并为ATN做出了贡献。