Johns Hopkins Adolescent Medicine Trials Unit

约翰霍普金斯大学青少年医学试验中心

• 批准号: 8257866
• 负责人: ALLISON L AGWU
• 金额: $ 34.71万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8257866
• 关键词: AIDS/HIV problem; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Affect; Baltimore; Child; Child health care; Childhood; Cities; Clinical; Collaborations; Communities; Community Health; Diagnosis; HIV; HIV Seropositivity; Health; IMPAACT; Institution; Intervention; Life; Medical; Pediatrics; Physician Executives; Prevention program; Principal Investigator; Qualifying; Recruitment Activity; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Risk; Site; Social Work; Syphilis; Universities; Work; Youth; aged; base; design; experience; forging; innovation; medical schools; outreach; pediatric department; professor; programs; psychosocial; success; treatment program; young adult

DESCRIPTION (provided by applicant): As of December 31, 2008, there were 252 children and adolescents aged 0-19 and 917 young adults aged 20- 29 with a reported HIV/AIDS diagnosis living in the city of Baltimore. The Pediatric and Adolescent HIV/AIDS Program (PAHAP) in the Johns Hopkins Children's Center in collaboration with its Center for Child and Community Health Research (CCHR) and the Adolescent Medicine Program is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The PAHAP offers comprehensive medical, psychosocial, outreach and social services to HIV-positive, HIV-affected, and at-risk adolescents in the context of a large, productive research institution located in East Baltimore City. The proposed Principal Investigator of the Johns Hopkins AMTU, Dr. Jonathan Ellen, is Professor and Vice Chair in the Department of Pediatrics at the Johns Hopkins University School of Medicine and is board certified in Pediatrics and Adolescent Medicine. He is Principal Investigator on the IMPAACT CTU site at Johns Hopkins and he co-directs PAHAP and the Adolescent Medicine Program. In addition to his work at these clinical programs, Dr. Ellen is Director of the CCHR. With his direction, the CCHR has designed and managed independent adolescent research projects and successfully participated in multi-site collaborative studies. The CCHR's infrastructure is responsible for many of the treatment and prevention programs provided in the PAHAP and the community. Further, in his capacity as Medical Director for the Baltimore City Health Department (HCHD) Syphilis Elimination Program, Dr. Ellen has forged a strong reciprocal relationship between the CCHR, PHAP and the BCHD that insures continued identification and referral of HIV-infected and at-risk adolescents and young adults to the PAHAP. Based on the combined expertise of the PAHAP and the CCHR, the use of innovative programs in reaching disenfranchised youth, demonstrated success in recruiting and retaining youth in trials, and productive collaborations with our community, we believe that the Johns Hopkins AMTU would offer significant operational and scientific contributions to the ATN agenda. RELEVANCE: The Pediatric and Adolescent HIV/AIDS Program (PAHAP) proposes to establish an Adolescent Medicine Trials Unit (ATU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The expertise of the investigators and experience of the staff make the PAHAP well qualified to be an effective ATU and contribute to the ATN.

描述（由申请人提供）：截至2008年12月31日，巴尔的摩市有252名0-19岁的儿童和青少年以及917名20- 29岁的年轻人被报告患有艾滋病毒/艾滋病。约翰霍普金斯儿童中心的儿童和青少年艾滋病毒/艾滋病项目（PAHAP）与其儿童和社区卫生研究中心（CCHR）和青少年医学项目合作，正在申请成为艾滋病毒/艾滋病干预青少年医学试验网络（ATN）的青少年医学试验单位（AMTU）。该计划在东巴尔的摩市的一个大型、富有成效的研究机构内，向艾滋病毒阳性、受艾滋病毒影响和有风险的青少年提供全面的医疗、心理社会、外联和社会服务。约翰霍普金斯大学AMTU的首席研究员Jonathan Ellen博士是约翰霍普金斯大学医学院儿科学教授和副主席，并获得儿科和青少年医学委员会认证。他是约翰霍普金斯大学impact CTU网站的首席研究员，并共同指导PAHAP和青少年医学项目。除了他在这些临床项目的工作之外，艾伦博士还是CCHR的主任。在他的指导下，CCHR设计并管理独立的青少年研究计划，并成功参与多地点的合作研究。CCHR的基础设施负责许多在PAHAP和社区提供的治疗和预防计划。此外，在担任巴尔的摩市卫生局（HCHD）梅毒消除项目的医疗主任期间，Ellen博士在CCHR、PHAP和BCHD之间建立了牢固的互惠关系，确保继续识别和转诊艾滋病毒感染和高危青少年和年轻人到PAHAP。基于PAHAP和CCHR的综合专业知识，利用创新的项目来接触被剥夺权利的年轻人，在招募和留住青年试验方面取得的成功，以及与我们社区的富有成效的合作，我们相信约翰霍普金斯大学的AMTU将为ATN议程提供重要的操作和科学贡献。