Viper Resource Center Supplement Proposal to Promote Diversity in Higher Education

国家天然毒素研究中心（NNTRC），德克萨斯A&M大学金斯维尔分校的一个组成部分 （TAMUK），是一个独特的动物和生物材料资源中心，组织起来，以支持基本和 对毒蛇及其毒液的转化研究。NNTRC致力于推动 在理解毒液分子的治疗价值和训练研究科学家方面， 毒理学领域自1978年成立以来，NNTRC已发展成为唯一的联邦政府 在美国资助的毒蛇资源中心，提供高质量的毒液和蛇相关的研究材料 国家和国际生物医学和生物研究计划。NNTRC的目标是 提供天然毒液、纯化的毒液组分、cDNA克隆和重组毒液蛋白， 质量最好的支持生物医学研究。为了实现这一目标，NNTRC将解决以下问题 具体目标： 目标#1将国家天然毒素研究中心作为一个资源中心， 优质毒液和产品，支持国家和国际生物和生物医学研究 研究项目。 目标2：发展和扩大蛇的收藏、专门服务、教育和宣传 支持美国毒液相关研究增长的计划。 目的#3为了支持使用高通量基因组的最先进的应用研究计划， 蛋白质组学、重组DNA和筛选技术，将支持基于信息的 发现具有潜在治疗和/或诊断作用的蛇毒成分的方法 应用. 在过去的五年中，NNTRC为促进这两个方面做出了重大贡献。 学术研究和药物和抗蛇毒治疗的商业开发。的 NNTRC的资源已应用于广泛学科和治疗领域的研究 从毒液进化的系统发育研究到伤害感受的转化研究， 止血，研究得到了多个NIH 1/C，NSF以及国家和国际 研究机构和基金会。除了作为毒液研究的国家资源和 作为一个毒理学研究中心，NNTRC也在提供机会方面发挥了重要作用， 在生物医学研究领域，教科文组织鼓励代表性不足的学生和教师接受培训。 相关性（参见说明）： NNTRC致力于支持科学家和研究人员从事新的研究， 基于蛇毒分子特性的疾病治疗方法。的发现 在NNTRC的支持下，他们正在为理解基本细胞过程的进展做出贡献 以及发现治疗癌症和凝血疾病的新方法。

The National Natural Toxins Research Center (NNTRC), a component of Texas A&M University-Kingsville (TAMUK), is a unique animal and biological material resource center organized to support basic and translational research on venomous snakes and their venoms. The NNTRC is dedicated to the advancement in the understanding of the therapeutic value of venom molecules and to the training of research scientists in the field of toxinology. Since its inception in 1978 the NNTRC has grown to become the only federally funded viper resource center in the U.S. providing high quality venom and snake-related research materials to national and international biomedical and biological research programs. Tiie goal of tiie NNTRC is to provide native venoms, purified venom components, cDNA clones, and recombinant venom proteins of tlie liighest quality to support biomedical researcli. To achieve this goal the NNTRC will address the following Specific Aims: Aim #1 To operate the National Natural Toxins Research Center as a resource center that provides high quality venom and products that support biological and biomedical research for national and International research programs. Aim #2 To develop and expand the collection of snakes, specialized services, education and outreach programs to support growth of venom-related research in the U.S. Aim #3 To support a state-of-the-art applied research program using high-throughput genomic, proteomic, recombinant DNA and screening technologies that will support an information-based approach to the discovery of snake venom components with potential therapeutic and/or diagnostic applications. In the preceding five years the NNTRC has made significant contributions to the advancement of both academic research and the commercial development of pharmaceutical and anti-venom therapeutics. The resources ofthe NNTRC have been applied to research in a wide range of disciplines and therapeutic areas ranging from phylogenetic studies onm venom evolution to translational research on nociception and hemostasis, research that has been supported by multiple NIH 1/C's, the NSF and national and international research agencies and foundations. In addition to its role as a national resource for venom research and as a center of toxinology research, the NNTRC has also played an important role in providing opportunities for underrepresented students and faculty to gain training in the field of biomedical research. RELEVANCE fSee instructions): The NNTRC is dedicated to the support of scientists and researchers engaged in the search for new treatments for disease based on the properties of molecules found in the snake venoms. Discoveries made with the support ofthe NNTRC are contributing to advances in the understanding of basic cellular processes as well as the discovery of new approaches for the treatment of cancer and blood clotting diseases.