Viper Resource Grant at Texas A&M University-Kingsville

国家天然毒素研究中心(NNTRC)，德克萨斯农工大学金斯维尔分校 (TAMUK)是一个独特的动物和生物材料资源中心，旨在支持基本和 关于毒蛇及其毒液的翻译研究。自2003年启动这项P40赠款以来， NNTRC一直是美国唯一由联邦政府资助的毒蛇资源中心，发挥着关键作用 提供高质量的单一来源的毒液和与蛇有关的研究材料给国家和 国际生物医学和生物研究计划。NNTRC的目标是为本地用户提供 蛇毒及纯化蛇毒成分、重组蛇毒蛋白及专门化蛇毒研究 提供最高质量的服务，支持国内外与蛇毒相关的研究 为了实现其目标，NNTRC将处理以下三个具体目标： 目标1将国家天然毒素研究中心作为一个资源中心运营，提供高质量的 支持国内和国际生物和生物医学研究的优质毒液和产品 研究项目。 目标#2发展和扩大蛇的收藏、专门服务和外联方案 以支持美国毒液相关研究的增长。 目标#3实施最先进的应用研究计划，以支持新技术的开发 与毒液相关的研究服务 为了实现这些目标，NNTRC组建了一支由熟练和经验丰富的科学家和研究人员组成的团队 在毒蛇管理以及收集和表征毒蛇方面具有专门知识的工作人员 蛇毒和抗蛇毒。它还收集了一系列全面的北美有毒物质 蛇，超过450只动物，代表21个不同的物种，由36个亚种组成，在 IACUC批准的条件在最先进的研究间隔室。NNTRC是公认的声誉良好的 提供与毒液相关的产品和专业服务的可靠来源，学术和 商业研究计划，以支持新药和抗蛇毒疗法的开发。 NNTRC的资源已被应用于广泛学科的研究，包括 毒液进化的基因组和蛋白质组学研究向伤害性和抗蛇毒的翻译研究 治疗，由多个NIH I/C、NSF、国防部和国家支持的研究 和国际研究机构。除了作为毒液研究的国家资源和作为 作为毒物学研究中心，NNTRC也发挥了重要作用，为 代表不足的学生和教职员工接受生物医学研究领域的培训。

The National Natural Toxins Research Center (NNTRC), a component of Texas A&M University–Kingsville (TAMUK), is a unique animal and biological material resource center organized to support basic and translational research on venomous snakes and their venoms. Since the initiation of this P40 grant in 2003, the NNTRC has served as the only federally-funded viper resource center in the U.S., playing a critical role as a provider of high quality single-source venoms and snake-related research materials to national and international biomedical and biological research programs. The goal of the NNTRC is to provide native venom and purified venom components, recombinant venom proteins and specialized venom research services of the highest quality to support snake venom – related research in the US and abroad To achieve its goal the NNTRC will address the following three Specific Aims: Aim #1 To operate the National Natural Toxins Research Center as a resource center that provides high quality venom and products that support biological and biomedical research for national and International research programs. Aim #2 To develop and expand the collection of snakes, specialized services and outreach programs to support growth of venom related research in the U.S. Aim #3 To conduct a state-of-the-art applied research program to support the development of new venom-related research services To address these aims the NNTRC has assembled a team of skilled and experienced scientists and research staff with specialized expertise in the management of venomous snakes and the collection and characterization of snake venoms and anti-venoms. It has also assembled a comprehensive collection of North American venomous snakes, more than 450 animals representing 21 different species consisting of 36 subspecies, maintained under IACUC-approved conditions in a state-of-the-art research vivarium. The NNTRC is recognized as a reputable and reliable source for both venom-related products and specialized services that are used by academic and commercial research programs to support the development of new drugs and anti-venom therapeutics. The resources of the NNTRC have been applied to research in a wide range of disciplines ranging from genomic and proteomic studies on venom evolution to translational research on nociception and anti-venom therapeutics, research that has been supported by multiple NIH I/C's, the NSF, Dept of Defense and national and international research agencies. In addition to its role as a national resource for venom research and as a center of toxinology research, the NNTRC has also played an important role in providing opportunities for underrepresented students and faculty to gain training in the field of biomedical research.