Surgery Research Training Program

项目概要/摘要 这项新的博士后培训计划的重点是教育临床科学家，主要是 外科医生和外科实习生，在技术和方法，包括翻译领域 研究和系统生物学。每名学员将与一名研究导师和一名职业导师联系， 将定期向学员提供指导和反馈。研究的“原材料”将是 作为丰富的正在进行的临床和转化研究的一部分获得的人类样本和数据 哈博维尤医学中心和华盛顿大学的项目。 我们之前的培训计划强调了“NIH路线图”中的“关键举措”，重点是 台架研究我们认识到，实验室研究对那些对以下内容感兴趣的潜在学员的吸引力较小： 追求临床科学家的学术生涯，比过去有更多的培训选择。我们 我们必须关注这一现实。重定向我们的计划是必要的，以鼓励有前途的和感兴趣的 研究创伤和危重病的生物学。在过去的10年里，我们的研究和 事实上，培训计划变得更加注重转化研究和系统生物学， 依赖于实验室研究我们还为学员提供了更有条理的教育（我们的大部分 最近的学员通过公共卫生学院获得硕士学位， 分子生物学、统计学和流行病学研究生课程。 通过这项申请，在未来5年内，我们将每年为一名学员提供以下核心课程： 高级培训的翻译研究方法和入学的华盛顿的学校的大学 公共卫生硕士课程我们将：（1）教育我们的研究员在先进的研究方法，通过配对 他们与积极的研究导师，他们选择的方案和资源。(2)增强他们的经验， 职业成功的可能性与获得研究和职业导师。(3)提供额外的教育 与转化健康科学研究所合作的机会。(4)努力建立一个真正 多样化的研究培训企业，这将减少生物医学研究的差距，并带来 多样性在我们的领域 概括来说，我们的研究培训计划的三条腿是：（1）我们的个人研究计划 和我们积累的经验提供了原材料和直接的经验（2）扩大的机会， 高级课程的工作，以获得硕士学位（3）一个制度环境，支持 生物医学研究教育，在负责任的研究行为和环境方面进行了强有力的培训 鼓励合作。

Project Summary/Abstract The focus of this proposed new post-doctoral training program is to educate clinician-scientists, primarily surgeons and surgical trainees, in the techniques and methods that comprise the fields of translational research and systems biology. Each trainee will be linked with a research mentor and a career mentor who will provide guidance and feedback on a regular basis to the trainee. The research “raw material” will be human samples and data that are obtained as part of the rich ongoing clinical and translational research programs at Harborview Medical Center and the University of Washington. Our previous training program emphasized “Key Initiatives” from the “NIH Roadmap” with a focus on bench research. We recognize that bench research is less appealing to potential trainees who are interested in pursuing an academic career as clinician-scientists and have more options for training than in the past. We must be attentive to this reality. Redirecting our program is necessary to encourage promising and interested surgeons to study the biology of trauma and critical illness. Over the past 10 years our research and research training programs have de facto become more focused on translational research and systems biology and less reliant on bench research. We have also provided our trainees with more structured education (most of our recent trainees have obtained a Master's degree through the school of public health and all have enrolled in graduate level courses in molecular biology, statistics and epidemiology. With this application and over the next 5 years, we will provide one trainee per year a core curriculum of advanced training in translational research methods and enrollment in the University of Washington's School of Public Health's master's program. We will: (1) Educate our fellows in advanced research methods, by pairing them with active research mentors, programs and resources of their choice. (2) Enhance their experience and likelihood of career success with access to research and career mentors. (3) Offer additional educational opportunities in collaboration with the Institute of Translational Health Sciences. (4) Strive to establish a truly diverse research training enterprise that will reduce disparity in biomedical research and bring the benefits of diversity to our field. In summary the three legs of our research training program are: (1) Our individual research programs and our cumulative experience provide the raw material and direct experience (2) Expanded opportunities for advanced course work in order to obtain a Master's degree (3) An institutional environment that supports biomedical research education with robust training in the responsible conduct of research and an environment encouraging collaboration.